dbacp04590
General Description
Peptide name : Mastoparan-L
Source/Organism : Venom, Common wasp
Linear/Cyclic : Not found
Chirality : Not found
Sequence Information
Sequence : INLKALAALAKKIL
Peptide length: 14
C-terminal modification: Not found
N-terminal modification : Not found
Non-natural peptide information: None
Activity Information
Assay type : Not specified
Assay time : Not found
Activity : Not found
Cell line : Not found
Cancer type : Not found
Other activity : Not found
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 1479.892 Dalton
Aliphatic index : 1.957
Instability index : 10.9143
Hydrophobicity (GRAVY) : 1.1571
Isoelectric point : 10.302
Charge (pH 7) : 2.7571
Aromaticity : 0
Molar extinction coefficient (cysteine, cystine): (0, 0)
Hydrophobic/hydrophilic ratio : 2.5
hydrophobic moment : -0.842
Missing amino acid : C,R,W,H,Q,T,P,M,E,F,S,D,Y,V,G
Most occurring amino acid : L
Most occurring amino acid frequency : 4
Least occurring amino acid : N
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (0.7, 0.0, 0.4)
SMILES Notation: CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)CC
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | HHHHHHHHHHHHHH |
| Chou-Fasman (CF) | HHHHHHHHHHHCCC |
| Neural Network (NN) | HHHHHHHHHHHHHH |
| Joint/Consensus | HHHHHHHHHHHHHH |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID : Not available
Reference
1 : Hirai Y, et al. A new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii. Chem Pharm Bull (Tokyo). 1979; 27:1942-4. doi: 10.1248/cpb.27.1942
Literature
Paper title : A new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii.
Doi : https://doi.org/10.1248/cpb.27.1942
Abstract : Not available