dbACP: A Comprehensive Database of Anti-Cancer Peptides

dbacp04590

General Description

Peptide name : Mastoparan-L

Source/Organism : Venom, Common wasp

Linear/Cyclic : Not found

Chirality : Not found

Sequence Information

Sequence : INLKALAALAKKIL

Peptide length: 14

C-terminal modification: Not found

N-terminal modification : Not found

Non-natural peptide information: None

Activity Information

Assay type : Not specified

Assay time : Not found

Activity : Not found

Cell line : Not found

Cancer type : Not found

Other activity : Not found

Physicochemical Properties

Amino acid composition bar chart :

Molecular mass : 1479.892 Dalton

Aliphatic index : 1.957

Instability index : 10.9143

Hydrophobicity (GRAVY) : 1.1571

Isoelectric point : 10.302

Charge (pH 7) : 2.7571

Aromaticity : 0

Molar extinction coefficient (cysteine, cystine): (0, 0)

Hydrophobic/hydrophilic ratio : 2.5

hydrophobic moment : -0.842

Missing amino acid : C,R,W,H,Q,T,P,M,E,F,S,D,Y,V,G

Most occurring amino acid : L

Most occurring amino acid frequency : 4

Least occurring amino acid : N

Least occurring amino acid frequency : 1

Structural Information

3D structure :

Secondary structure fraction (Helix, Turn, Sheet): (0.7, 0.0, 0.4)

SMILES Notation: CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)CC

Secondary Structure :

Method Prediction
GOR HHHHHHHHHHHHHH
Chou-Fasman (CF) HHHHHHHHHHHCCC
Neural Network (NN) HHHHHHHHHHHHHH
Joint/Consensus HHHHHHHHHHHHHH

Molecular Descriptors and ADMET Properties

Molecular Descriptors: Click here to download

ADMET Properties: Click here to download

Cross Referencing databases

Pubmed Id : 540362

Uniprot : Not available

PDB : Not available

CancerPPD : Not available

ApIAPDB : Not available

CancerPPD2 ID : Not available

Reference

1 : Hirai Y, et al. A new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii. Chem Pharm Bull (Tokyo). 1979; 27:1942-4. doi: 10.1248/cpb.27.1942

Literature

Paper title : A new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii.

Doi : https://doi.org/10.1248/cpb.27.1942

Abstract : Not available