dbACP: A Comprehensive Database of Anti-Cancer Peptides

dbacp05970

General Description

Peptide name : RGSALTHLP

Source/Organism : Siamese crocodile Leukocyte

Linear/Cyclic : Not found

Chirality : Not found

Sequence Information

Sequence : RGSALTHLP

Peptide length: 9

C-terminal modification: Not found

N-terminal modification : Not found

Non-natural peptide information: None

Activity Information

Assay type : Sulforhodamine B colorimetric assay

Assay time : 24h

Activity : IC50 : 168.33 ± 1.6 μM

Cell line : CaSki

Cancer type : Cervical cancer

Other activity : Not found

Physicochemical Properties

Amino acid composition bar chart :

Molecular mass : 951.0811 Dalton

Aliphatic index : 0.977

Instability index : 20.8556

Hydrophobicity (GRAVY) : -0.2

Isoelectric point : 9.7565

Charge (pH 7) : 0.8473

Aromaticity : 0

Molar extinction coefficient (cysteine, cystine): (0, 0)

Hydrophobic/hydrophilic ratio : 1.25

hydrophobic moment : 0.6179

Missing amino acid : C,W,Q,M,I,E,K,F,D,Y,N,V

Most occurring amino acid : L

Most occurring amino acid frequency : 2

Least occurring amino acid : R

Least occurring amino acid frequency : 1

Structural Information

3D structure :

Secondary structure fraction (Helix, Turn, Sheet): (0.3, 0.3, 0.3)

SMILES Notation: CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)O

Secondary Structure :

Method Prediction
GOR TTTEEEECC
Chou-Fasman (CF) CCCCCCCCC
Neural Network (NN) CCCCCCCCC
Joint/Consensus CCCCCCCCC

Molecular Descriptors and ADMET Properties

Molecular Descriptors: Click here to download

ADMET Properties: Click here to download

Cross Referencing databases

Pubmed Id : RP9

Uniprot : Not available

PDB : Not available

CancerPPD : Not available

ApIAPDB : Not available

CancerPPD2 ID : Not available

Reference

Literature