dbacp06182
General Description
Peptide name : Synthetic peptide
Source/Organism : Synthetic peptide
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : KWKKLLKKPPPLLKKLLKKL
Peptide length: 20
C-terminal modification: Linear
N-terminal modification : Free
Non-natural peptide information: None
Activity Information
Assay type : MTT/MTS assay
Assay time : Not found
Activity : 0% survival rate at 100 µM
Cell line : SNU-601
Cancer type : Gastric cancer
Other activity : Not found
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 2441.2247 Dalton
Aliphatic index : 1.365
Instability index : -0.48
Hydrophobicity (GRAVY) : -0.71
Isoelectric point : 10.903
Charge (pH 7) : 8.7511
Aromaticity : 0.05
Molar extinction coefficient (cysteine, cystine): (5500, 5500)
Hydrophobic/hydrophilic ratio : 1.22222222
hydrophobic moment : -0.329
Missing amino acid : T,I,M,E,F,D,N,G,C,R,H,Q,S,Y,A,V
Most occurring amino acid : K
Most occurring amino acid frequency : 9
Least occurring amino acid : W
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (0.8, 0.1, 0.4)
SMILES Notation: CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCCN)C(=O)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | HHHHHTTCCCCHHHHHHHHH |
| Chou-Fasman (CF) | HHHHHHCCCCHHHHHHHCCC |
| Neural Network (NN) | HHHCCCCCCCCHHHHHHHHH |
| Joint/Consensus | HHHHHCCCCCCHHHHHHHHH |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download