dbacp06523
General Description
Peptide name : Viscotoxin A3
Source/Organism : The European mistletoe
Linear/Cyclic : Not found
Chirality : L
Sequence Information
Sequence : KSCCPNTTGRNIYNACRLTGAPRPTCAKLSGCKIISGSTCPSDYPK
Peptide length: 46
C-terminal modification: Not found
N-terminal modification : Free
Non-natural peptide information: None
Activity Information
Assay type : Not specified
Assay time : Not found
Activity : Not found
Cell line : Not found
Cancer type : Breast cancer
Other activity : Not found
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 4835.5695 Dalton
Aliphatic index : 0.489
Instability index : 49.5609
Hydrophobicity (GRAVY) : -0.463
Isoelectric point : 9.3029
Charge (pH 7) : 5.6958
Aromaticity : 0.043
Molar extinction coefficient (cysteine, cystine): (2980, 3355)
Hydrophobic/hydrophilic ratio : 1
hydrophobic moment : 0.304
Missing amino acid : W,H,Q,M,E,F,V
Most occurring amino acid : C
Most occurring amino acid frequency : 6
Least occurring amino acid : D
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (0.2, 0.3, 0.2)
SMILES Notation: CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | TTTCTTTCCCEEEETEEETTCCCCCCTTTTTEEEEETCCCCCCCCT |
| Chou-Fasman (CF) | CCCCCEECEEEECCCEEECCCCCCCCCCCCEEEEEEECCCCCCCCC |
| Neural Network (NN) | CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCC |
| Joint/Consensus | CCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCC |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID : Not available
Reference
1 : Samuelsson G, et al. The amino acid sequence of oxidized viscotoxin A3 from the European mistletoe (Viscum album L, Loranthaceae). Acta Chem Scand. 1968; 22:2624-42. doi: 10.3891/acta.chem.scand.22-2624
Literature
Paper title : The amino acid sequence of oxidized viscotoxin A3 from the European mistletoe (Viscum album L, Loranthaceae).
Doi : https://doi.org/10.3891/acta.chem.scand.22-2624
Abstract : Not available