dbACP: A Comprehensive Database of Anti-Cancer Peptides

dbacp06547

General Description

Peptide name : YALRAH

Source/Organism : Not found

Linear/Cyclic : Linear

Chirality : L

Sequence Information

Sequence : YALRAH

Peptide length: 6

C-terminal modification: Linear

N-terminal modification : Not found

Non-natural peptide information: None

Activity Information

Assay type : Not specified

Assay time : Not found

Activity : IC50 : 8.1 mg/ml

Cell line : PC-3

Cancer type : Not found

Other activity : Not found

Physicochemical Properties

Amino acid composition bar chart :

Molecular mass : 729.8269 Dalton

Aliphatic index : 0.983

Instability index : 65.75

Hydrophobicity (GRAVY) : -0.266

Isoelectric point : 8.7548

Charge (pH 7) : 0.8463

Aromaticity : 0.166

Molar extinction coefficient (cysteine, cystine): (1490, 1490)

Hydrophobic/hydrophilic ratio : 1

hydrophobic moment : -0.600

Missing amino acid : C,W,Q,T,P,M,I,E,K,S,D,F,N,V,G

Most occurring amino acid : A

Most occurring amino acid frequency : 2

Least occurring amino acid : Y

Least occurring amino acid frequency : 1

Structural Information

3D structure :

Secondary structure fraction (Helix, Turn, Sheet): (0.5, 0, 0.3)

SMILES Notation: CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

Secondary Structure :

Method Prediction
GOR HHHHHH
Chou-Fasman (CF) CCCCCC
Neural Network (NN) HHHHHH
Joint/Consensus HHHHHH

Molecular Descriptors and ADMET Properties

Molecular Descriptors: Click here to download

ADMET Properties: Click here to download

Cross Referencing databases

Pubmed Id : 38807612

Uniprot : Not available

PDB : Not available

CancerPPD : Not available

ApIAPDB : Not available

CancerPPD2 ID : Not available

Reference

1 : Shawcroft J, et al. Corrigendum/Erratum to "Teens, screens and quarantine; The relationship between adolescent media use and mental health prior to and during COVID-19" [Heliyon 8(7), July 2022 e09898]. Heliyon. 2024; 10:e30236. doi: 10.1016/j.heliyon.2024.e30236

Literature

Paper title : Corrigendum/Erratum to "Teens, screens and quarantine; The relationship between adolescent media use and mental health prior to and during COVID-19" [Heliyon 8(7), July 2022 e09898].

Doi : https://doi.org/10.1016/j.heliyon.2024.e30236

Abstract : [This corrects the article DOI: 10.1016/j.heliyon.2022.e09898.].