dbacp06547
General Description
Peptide name : YALRAH
Source/Organism : Not found
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : YALRAH
Peptide length: 6
C-terminal modification: Linear
N-terminal modification : Not found
Non-natural peptide information: None
Activity Information
Assay type : Not specified
Assay time : Not found
Activity : IC50 : 8.1 mg/ml
Cell line : PC-3
Cancer type : Not found
Other activity : Not found
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 729.8269 Dalton
Aliphatic index : 0.983
Instability index : 65.75
Hydrophobicity (GRAVY) : -0.266
Isoelectric point : 8.7548
Charge (pH 7) : 0.8463
Aromaticity : 0.166
Molar extinction coefficient (cysteine, cystine): (1490, 1490)
Hydrophobic/hydrophilic ratio : 1
hydrophobic moment : -0.600
Missing amino acid : C,W,Q,T,P,M,I,E,K,S,D,F,N,V,G
Most occurring amino acid : A
Most occurring amino acid frequency : 2
Least occurring amino acid : Y
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (0.5, 0, 0.3)
SMILES Notation: CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | HHHHHH |
| Chou-Fasman (CF) | CCCCCC |
| Neural Network (NN) | HHHHHH |
| Joint/Consensus | HHHHHH |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID : Not available
Reference
1 : Shawcroft J, et al. Corrigendum/Erratum to "Teens, screens and quarantine; The relationship between adolescent media use and mental health prior to and during COVID-19" [Heliyon 8(7), July 2022 e09898]. Heliyon. 2024; 10:e30236. doi: 10.1016/j.heliyon.2024.e30236
Literature
Paper title : Corrigendum/Erratum to "Teens, screens and quarantine; The relationship between adolescent media use and mental health prior to and during COVID-19" [Heliyon 8(7), July 2022 e09898].
Doi : https://doi.org/10.1016/j.heliyon.2024.e30236
Abstract : [This corrects the article DOI: 10.1016/j.heliyon.2022.e09898.].