dbacp08297
General Description
Peptide name : DN1
Source/Organism : Synthetic
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : ILGKIVKKLVSDF
Peptide length: 13
C-terminal modification: Linear
N-terminal modification : Free
Non-natural peptide information:
Activity Information
Assay type : MTT assay
Assay time : 24-h
Activity : 152.17 ± 7.73 μM
Cell line : HepG-2
Cancer type : Liver Cancer
Other activity : Antimicrobial
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 1459.8144 Dalton
Aliphatic index : 1.646
Instability index : -10.092
Hydrophobicity (GRAVY) : 0.8769
Isoelectric point : 9.703
Charge (pH 7) : 1.7582
Aromaticity : 7.692
Molar extinction coefficient (cysteine, cystine): (0, 0)
Hydrophobic/hydrophilic ratio : 1.6
hydrophobic moment : -0.583
Missing amino acid : A,C,E,H,M,N,P,Q,R,T,W,Y
Most occurring amino acid : K
Most occurring amino acid frequency : 3
Least occurring amino acid : G
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (38., 23., 53.)
SMILES Notation: CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C)C(C)C)[C@@H](C)CC
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | HHHHHHHEEEEHH |
| Chou-Fasman (CF) | EEEEECCEEECCC |
| Neural Network (NN) | HHCHHHHHCCCCC |
| Joint/Consensus | CCCHHHHEEECCC |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
Pubmed Id :
Uniprot : Not available
PDB : Not available
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID: 6658