dbacp08301
General Description
Peptide name : SKACP003
Source/Organism : Synthetic
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : FPLPCAYKGTYC
Peptide length: 12
C-terminal modification: Linear
N-terminal modification : Free
Non-natural peptide information:
Activity Information
Assay type : MTT assay
Assay time : 24-h
Activity : IC50 = 156 ± 0.5 µM
Cell line : MDA-MB-453
Cancer type : Breast Cancer
Other activity : Anticancer
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 1362.6147 Dalton
Aliphatic index : 0.408
Instability index : 20.8333
Hydrophobicity (GRAVY) : 0.2167
Isoelectric point : 8.0329
Charge (pH 7) : 0.7373
Aromaticity : 25
Molar extinction coefficient (cysteine, cystine): (2, 1)
Hydrophobic/hydrophilic ratio : 2
hydrophobic moment : -0.084
Missing amino acid : D,E,H,I,M,N,Q,R,S,V,W
Most occurring amino acid : P
Most occurring amino acid frequency : 2
Least occurring amino acid : F
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (24., 25, 41.)
SMILES Notation: CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)O)[C@@H](C)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | CCCTTTTTTCEE |
| Chou-Fasman (CF) | CCCCCCEEECCC |
| Neural Network (NN) | CCCCCCCCCCCC |
| Joint/Consensus | CCCCCCCCCCCC |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
Pubmed Id :
Uniprot : Not available
PDB : Not available
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID: 6837