dbacp08302
General Description
Peptide name : RF13
Source/Organism : VSP26B of C. striatus
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : RRGKGGRRVTMSF
Peptide length: 13
C-terminal modification: Linear
N-terminal modification : Free
Non-natural peptide information:
Activity Information
Assay type : MTT assay
Assay time : 24-h
Activity : IC50 = 49.65 µM
Cell line : HEp-2
Cancer type : Larynx Cancer
Other activity : Anticancer
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 1507.7663 Dalton
Aliphatic index : 0.223
Instability index : 114.523
Hydrophobicity (GRAVY) : -1.207
Isoelectric point : 12
Charge (pH 7) : 4.7591
Aromaticity : 7.692
Molar extinction coefficient (cysteine, cystine): (0, 0)
Hydrophobic/hydrophilic ratio : 0.8571
hydrophobic moment : -0.589
Missing amino acid : A,C,D,E,H,I,L,N,P,Q,W,Y
Most occurring amino acid : R
Most occurring amino acid frequency : 4
Least occurring amino acid : K
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (15., 30., 23.)
SMILES Notation: CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | HTTTTCCEEEEEE |
| Chou-Fasman (CF) | CCCCCEEEEECCC |
| Neural Network (NN) | CCCCCCCEEEEEE |
| Joint/Consensus | CCCCCCCEEEEEE |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
Pubmed Id :
Uniprot : Not available
PDB : Not available
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID: 7313