dbacp08315
General Description
Peptide name : P1B
Source/Organism : Synthetic
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : YKSVEFC
Peptide length: 7
C-terminal modification: Linear
N-terminal modification : Acetylation
Non-natural peptide information:
Activity Information
Assay type : Cell Proliferation assay
Assay time : 72-h
Activity : ~50% reduction in cell growth at 20 μM
Cell line : BXPC-5
Cancer type : Pancreatic Cancer
Other activity : Anticancer
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 874.9998 Dalton
Aliphatic index : 0.414
Instability index : 8.5714
Hydrophobicity (GRAVY) : 0
Isoelectric point : 5.9936
Charge (pH 7) : -0.249
Aromaticity : 28.57
Molar extinction coefficient (cysteine, cystine): (1, 0)
Hydrophobic/hydrophilic ratio : 0.75
hydrophobic moment : -0.549
Missing amino acid : A,D,G,H,I,L,M,N,P,Q,R,T,W
Most occurring amino acid : Y
Most occurring amino acid frequency : 1
Least occurring amino acid : Y
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (28., 14., 42.)
SMILES Notation: CC(C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | TTTEHEH |
| Chou-Fasman (CF) | CCCCCCC |
| Neural Network (NN) | CCCCEEE |
| Joint/Consensus | CCCCCCC |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
Pubmed Id :
Uniprot : Not available
PDB : Not available
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID: 7810