dbacp08325
General Description
Peptide name : Sample Peptide 6 from US011339203B2
Source/Organism : Synthetic
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : VIIVLSVFIACWAPLFILLLLKKRTLRKNDRKKR
Peptide length: 34
C-terminal modification: Linear
N-terminal modification : Amidation
Non-natural peptide information:
Activity Information
Assay type : CCK-8 assay
Assay time : 48-h
Activity : Cell Viability = 59.7% at 25 μM
Cell line : CAKI-2
Cancer type : Renal Cancer
Other activity : Anticancer
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 4066.0888 Dalton
Aliphatic index : 1.576
Instability index : 54.1324
Hydrophobicity (GRAVY) : 0.6
Isoelectric point : 11.593
Charge (pH 7) : 7.7202
Aromaticity : 8.823
Molar extinction coefficient (cysteine, cystine): (1, 0)
Hydrophobic/hydrophilic ratio : 1.6154
hydrophobic moment : 0.1437
Missing amino acid : E,G,H,M,Q,Y
Most occurring amino acid : L
Most occurring amino acid frequency : 7
Least occurring amino acid : S
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (41., 11., 52.)
SMILES Notation: CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(C)C)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@@H](C)O)[C@@H](C)CC
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | EEEEEEEEHHHHCHHHHHHHHHHHHHHHHHHTHH |
| Chou-Fasman (CF) | EEEEEEEEECCCCEEEEHHHHHHCHHHHHHHCCC |
| Neural Network (NN) | EEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCC |
| Joint/Consensus | EEEEEEEEHHHHCHHHHHHHHHHHHHHHHHHCCC |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
Pubmed Id :
Uniprot : Not available
PDB : Not available
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID: 7821