Peptide name : Sample Peptide 2 from EP3604345B1

Source/Organism : Synthetic

Linear/Cyclic : Linear

Chirality : L

Peptide length: 29

C-terminal modification: Linear

N-terminal modification : Amidation

Non-natural peptide information:

Assay type : CCK-8 / WST-8

Assay time : 48-h

Activity : Cell Viability = 3.6% at 25 μM

Cell line : NCI-H2444

Cancer type : Lung Cancer

Other activity : Anticancer

Amino acid composition bar chart :

Molecular mass : 3697.4208 Dalton

Aliphatic index : 0.772

Instability index : 132.196

Hydrophobicity (GRAVY) : -1.069

Isoelectric point : 12

Charge (pH 7) : 8.4983

Aromaticity : 10.34

Molar extinction coefficient (cysteine, cystine): (0, 0)

Hydrophobic/hydrophilic ratio : 1.2308

hydrophobic moment : -0.453

Missing amino acid : C,D,E,F,H,N,S,T,Y

Most occurring amino acid : R

Most occurring amino acid frequency : 7

Least occurring amino acid : M

Least occurring amino acid frequency : 1

Secondary structure fraction (Helix, Turn, Sheet): (24., 13., 31.)

SMILES Notation: CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C)C(C)C)C(C)C