dbACP: A Comprehensive Database of Anti-Cancer Peptides

dbacp08349

General Description

Peptide name : LPSBD-0

Source/Organism : Synthetic

Linear/Cyclic : Linear

Chirality : L

Sequence Information

Sequence : CQYSVNPKIKRFELYFKGRMW

Peptide length: 21

C-terminal modification: Linear

N-terminal modification : Free

Non-natural peptide information:

Activity Information

Assay type : Not Available

Assay time : 24-h

Activity : Not Available

Cell line : THP-1

Cancer type : Leukemia Cancer

Other activity : Anticancer

Physicochemical Properties

Amino acid composition bar chart :

Molecular mass : 2694.1822 Dalton

Aliphatic index : 0.509

Instability index : -2.7905

Hydrophobicity (GRAVY) : -0.714

Isoelectric point : 9.8635

Charge (pH 7) : 3.748

Aromaticity : 23.80

Molar extinction coefficient (cysteine, cystine): (1, 0)

Hydrophobic/hydrophilic ratio : 0.9091

hydrophobic moment : 0.5946

Missing amino acid : A,D,H,T

Most occurring amino acid : K

Most occurring amino acid frequency : 3

Least occurring amino acid : C

Least occurring amino acid frequency : 1

Structural Information

3D structure :

Secondary structure fraction (Helix, Turn, Sheet): (28., 19., 38.)

SMILES Notation: CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CS)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

Secondary Structure :

Method Prediction
GOR EETTTCCTHHHHHHHHTTHHH
Chou-Fasman (CF) EEECCCCCCHHHHEECCCCCC
Neural Network (NN) CCCCCCCCCHHHHHHHHCCCC
Joint/Consensus EECCCCCCCHHHHHHHCCCCC

Molecular Descriptors and ADMET Properties

Molecular Descriptors: Click here to download

ADMET Properties: Click here to download

Cross Referencing databases

Pubmed Id :

Uniprot : Not available

PDB : Not available

CancerPPD : Not available

ApIAPDB : Not available

CancerPPD2 ID: 6207

Reference

Literature