dbacp08350
General Description
Peptide name : LPSBD-2
Source/Organism : Synthetic
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : CHYRVKPKIKRFEKYKGRMW
Peptide length: 20
C-terminal modification: Linear
N-terminal modification : Free
Non-natural peptide information:
Activity Information
Assay type : Not Available
Assay time : 24-h
Activity : Not Available
Cell line : THP-1
Cancer type : Leukemia Cancer
Other activity : Anticancer
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 2654.2113 Dalton
Aliphatic index : 0.34
Instability index : 37.67
Hydrophobicity (GRAVY) : -1.465
Isoelectric point : 10.388
Charge (pH 7) : 6.8332
Aromaticity : 20
Molar extinction coefficient (cysteine, cystine): (1, 0)
Hydrophobic/hydrophilic ratio : 0.6667
hydrophobic moment : 0.8452
Missing amino acid : A,D,L,N,Q,S,T
Most occurring amino acid : K
Most occurring amino acid frequency : 5
Least occurring amino acid : C
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (35, 10, 30)
SMILES Notation: CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CS)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | HHHTTCTHHHHHHHHTTHHH |
| Chou-Fasman (CF) | EEECCCCCCHHHHCCCCCCC |
| Neural Network (NN) | CCCCCCCCCCHHHHHCCCCE |
| Joint/Consensus | CCCCCCCCCHHHHHHCCCCC |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
Pubmed Id :
Uniprot : Not available
PDB : Not available
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID: 6208