dbacp08371
General Description
Peptide name : IDP-NS10
Source/Organism : Synthetic
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : AALVVILKKATEYVHS
Peptide length: 16
C-terminal modification: Linear
N-terminal modification : Free
Non-natural peptide information: -(CH2)6-CH=CH-(CH2)3
Activity Information
Assay type : AlamarBlue assay
Assay time : 72-96 h
Activity : EC50 ~ 50 μM
Cell line : 12053
Cancer type : Glioblastoma
Other activity : Anticancer
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 1742.0671 Dalton
Aliphatic index : 1.462
Instability index : 28.1438
Hydrophobicity (GRAVY) : 0.8
Isoelectric point : 8.5472
Charge (pH 7) : 0.8829
Aromaticity : 6.25
Molar extinction coefficient (cysteine, cystine): (0, 0)
Hydrophobic/hydrophilic ratio : 1.2857
hydrophobic moment : -1.067
Missing amino acid : C,D,F,G,M,N,P,Q,R,W
Most occurring amino acid : A
Most occurring amino acid frequency : 3
Least occurring amino acid : I
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (50, 6.2, 50)
SMILES Notation: CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](C)N)C(C)C)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)O)C(C)C)[C@@H](C)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | HHHHHHHHHHHHEEEE |
| Chou-Fasman (CF) | CEEEEHHHHHEEECCC |
| Neural Network (NN) | HHHHHHHHHCHHHHHC |
| Joint/Consensus | HHHHHHHHHHHHCCCC |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
Pubmed Id :
Uniprot : Not available
PDB : Not available
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID: 7735