dbacp08375
General Description
Peptide name : IDP-Na05
Source/Organism : Synthetic
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : RRNDLRSSFLTLRDHVP
Peptide length: 17
C-terminal modification: Linear
N-terminal modification : Free
Non-natural peptide information: -(CH2)6-CH=CH-(CH2)3
Activity Information
Assay type : AlamarBlue assay
Assay time : 72-96 h
Activity : EC50 ~ 10 μM
Cell line : RG1
Cancer type : Glioblastoma
Other activity : Anticancer
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 2082.3261 Dalton
Aliphatic index : 0.858
Instability index : 121.529
Hydrophobicity (GRAVY) : -1.011
Isoelectric point : 11.523
Charge (pH 7) : 1.8495
Aromaticity : 5.882
Molar extinction coefficient (cysteine, cystine): (0, 0)
Hydrophobic/hydrophilic ratio : 0.5455
hydrophobic moment : 0.5909
Missing amino acid : A,C,E,G,I,K,M,Q,W,Y
Most occurring amino acid : R
Most occurring amino acid frequency : 4
Least occurring amino acid : N
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (17., 35., 35.)
SMILES Notation: CC(C)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)C(C)C)[C@@H](C)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | HTTTTTTTEEEEETTCC |
| Chou-Fasman (CF) | CCCCCEEEEECCCCCCC |
| Neural Network (NN) | CCCCCCHHHCCHCCCCC |
| Joint/Consensus | CCCCCCCCEECCCCCCC |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
Pubmed Id :
Uniprot : Not available
PDB : Not available
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID: 7739