dbacp08436
General Description
Peptide name : Alpha-gliadin peptide p31-43
Source/Organism : Synthetic
Linear/Cyclic : Linear
Chirality : L
Sequence Information
Sequence : LGQQQPFPPQQPY
Peptide length: 13
C-terminal modification: Linear
N-terminal modification : Free
Non-natural peptide information:
Activity Information
Assay type : TUNEL assay
Assay time : 72-h
Activity : Mean apoptotic rate = 36% at 200 μg/mL
Cell line : A-549
Cancer type : Lung Cancer
Other activity : Anticancer
Physicochemical Properties
Amino acid composition bar chart :
Molecular mass : 1527.678 Dalton
Aliphatic index : 0.3
Instability index : 142.569
Hydrophobicity (GRAVY) : -1.461
Isoelectric point : 5.5243
Charge (pH 7) : -0.2409
Aromaticity : 15.38
Molar extinction coefficient (cysteine, cystine): (0, 0)
Hydrophobic/hydrophilic ratio : 1.1667
hydrophobic moment : 0.2162
Missing amino acid : A,C,D,E,H,I,K,M,N,R,S,T,V,W
Most occurring amino acid : Q
Most occurring amino acid frequency : 5
Least occurring amino acid : L
Least occurring amino acid frequency : 1
Structural Information
3D structure :
Secondary structure fraction (Helix, Turn, Sheet): (7.6, 38., 23.)
SMILES Notation: CC(C)C[C@H](N)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O
Secondary Structure :
| Method | Prediction |
|---|---|
| GOR | CCCCCCCCCCCCC |
| Chou-Fasman (CF) | CCCCCCCCCCCCC |
| Neural Network (NN) | CCCCCCCCCCCCC |
| Joint/Consensus | CCCCCCCCCCCCC |
Molecular Descriptors and ADMET Properties
Molecular Descriptors: Click here to download
ADMET Properties: Click here to download
Cross Referencing databases
Pubmed Id :
Uniprot : Not available
PDB : Not available
CancerPPD : Not available
ApIAPDB : Not available
CancerPPD2 ID: 7814