dbACP: A Comprehensive Database of Anti-Cancer Peptides

24 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp02272 Camel KWKLFKKIGAVLKVL Ceropin-Melittin hybrid Cell swelling and rupture of the plasma membrane MTT/MTS assay 4T1 Breast cancer LC50 : 6.2 µM
dbacp04925 NRC-03 GRRKRKWLRRIGKGVKIIGGAALDHL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 15-20% Cytotoxic at 5 µM
dbacp04926 NRC-03 GRRKRKWLRRIGKGVKIIGGAALDHL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 40-50% Cytotoxic at 10 µM
dbacp04927 NRC-03 GRRKRKWLRRIGKGVKIIGGAALDHL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 80% Cytotoxic at 25 µM
dbacp04928 NRC-03 GRRKRKWLRRIGKGVKIIGGAALDHL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 85-90% Cytotoxic at 50 µM
dbacp04948 NRC-03 GRRKRKWLRRIGKGVKIIGGAALDHL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 15-20% Cytotoxic at 5 µM
dbacp04949 NRC-03 GRRKRKWLRRIGKGVKIIGGAALDHL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 40-50% Cytotoxic at 10 µM
dbacp04950 NRC-03 GRRKRKWLRRIGKGVKIIGGAALDHL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 80% Cytotoxic at 25 µM
dbacp04951 NRC-03 GRRKRKWLRRIGKGVKIIGGAALDHL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 85-90% Cytotoxic at 50 µM
dbacp04970 NRC-07 RWGKWFKKATHVGKHVGKAALTAYL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 30-40% Cytotoxic at 5 µM
dbacp04971 NRC-07 RWGKWFKKATHVGKHVGKAALTAYL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 60-70% Cytotoxic at 10 µM
dbacp04972 NRC-07 RWGKWFKKATHVGKHVGKAALTAYL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 80-90% Cytotoxic at 25 µM
dbacp04973 NRC-07 RWGKWFKKATHVGKHVGKAALTAYL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 85-90% Cytotoxic at 50 µM
dbacp04992 NRC-13 GWRTLLKKAEVKTVGKLALKHYL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer ~0% Cytotoxic at 5 µM
dbacp04993 NRC-13 GWRTLLKKAEVKTVGKLALKHYL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer ~0% Cytotoxic at 10 µM
dbacp04994 NRC-13 GWRTLLKKAEVKTVGKLALKHYL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 5-10% Cytotoxic at 25 µM
dbacp04995 NRC-13 GWRTLLKKAEVKTVGKLALKHYL Skin mucous secretion of winter flounder Cell membrane damage MTT/MTS assay 4T1 Breast cancer 20% Cytotoxic at 50 µM
dbacp05865 RA-V cyclopeptideRA-V-,cyclo(YAAYAY) Plant sources Inducing apoptosis MTT assay 4T1 Breast cancer Not found
dbacp06128 Smac-CPP AVPIAQKSVSRRRRRRGGRRRR SMAC Inducing apoptosis Not specified 4T1 Not found IC50 : 132 μM
dbacp07309 LyeTxI-b IWLTALKFLGKNLGKLAKQQLAKL Synthetic Apoptosis induction and immune modulation. MTT assay 4T1 Breast Cancer IC50 = 6.5 ± 5.30 µM
dbacp07864 HN-1 FALGAVTKLLPSLLCMITRKC Amolops hainanensis Apoptosis induction and immune activation MTT assay 4T1 Breast Cancer Not Available
dbacp08049 Temporin-1Ga SILPTIVSFLSKVF Synthetic Temporin-1OLa disrupts bacterial membranes MTS assay 4T1 Breast Cancer LC50 = 20 μM
dbacp08050 Temporin-CPa IPPFIKKVLTTVF Synthetic Temporin-1OLa disrupts bacterial membranes MTS assay 4T1 Breast Cancer LC50 = 80 μM
dbacp08063 E5 GGRSFFLLRRIQGCRFRNTVDD Synthetic E5 inhibits CXCR4–CXCL12 signaling CCK-8 assay 4T1 Breast Cancer 49% cell viability at 100 μM