dbACP: A Comprehensive Database of Anti-Cancer Peptides

6 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp01364 Aurein-3.1 [Cleaved into: Aurein-3.1.1; Aurein-3.1.2] GLFDIVKKIAGHIAGSI Southern bell frog Cell membrane disintegration One-dose and five-dose assay 786-0 Renal cancer IC50 : 5 μM
dbacp02025 Buforin IIb RAGLQFPVGRLLRRLLRRLLR Histone H2A Inducing mitochondria-dependent apoptosis MTT/MTS assay 786-0 Renal cancer IC50 : 12.2 µg/ml
dbacp02083 Buforin Iib RAGLQFPVGRLLRRLLRRLLR Not found Inducing apoptosis MTT/MTS assay 786-0 Not specified IC50 : 12.2 µg/ml
dbacp06156 StigA16 FFKLIPKLVKGLISAF Amino acid substitution, amino acid truncation, animal-derived, natural derivative Disruption of cell membrane MTT assay 786-0 Human cervix adenocarcinoma IC 50 : 13.01 μM
dbacp06161 StigA6 FFSLIPKLVKGLISAFK Amino acid substitution, animal-derived, natural derivative Disruption of cell membrane MTT assay 786-0 Human cervix adenocarcinoma IC 50 : 14.01 μM
dbacp06766 M1-21 rrrqrrkkrg-QTQPRLGPPQTPAGGCSILIF Synthetic FOXM1 inhibitor Cell Viability assay 786-0 Renal Cancer IC50 = 13.5 µM