20 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01440 | BAA-1 | NA | Bovine lactoferrin (Lf-B) | Destabilizing the cell membrane | MTT/MTS assay | Ramos | Lymphoma cancer | IC50 : 8.1 µg/ml |
| dbacp01441 | BAA-2 | NA | Bovine lactoferrin (Lf-B) | Apoptosis inducing | MTT/MTS assay | Ramos | Lymphoma cancer | IC50 : 3.8 µg/ml |
| dbacp03375 | IL-4Rα-lytic hybrid peptide | KQLIRFLKRLDRNGGGKLlLKlLkkLLKlLKKK | Bovine lactoferrin (Lf-B) | Induction of apoptosis | WST-1 assay | KB | Oral cancer | IC50 : 13.2 µMol/L |
| dbacp03529 | KW5 | KAAKKAAKAAKKAAKAAKKAA | Bovine lactoferrin (Lf-B) | Through interactions with the plasma membrane | MTT/MTS assay | FEMX | Skin cancer | IC50 : 30 ± 3 µM |
| dbacp03730 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | HT-29 | Colon cancer | IC50 : > 160 µM |
| dbacp03731 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | MT-1 | Breast cancer | IC50 : > 160 µM |
| dbacp03732 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | Kelly | Brain tumor | IC50 : 141 ± 3 µM |
| dbacp03733 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | FEMX | Skin cancer | IC50 : 40 ± 7 µM |
| dbacp03734 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | HT-29 | Colon cancer | IC50 : 148 ± 8 µM |
| dbacp03735 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | KMS-5 | Skin cancer | IC50 : 38 µM |
| dbacp03736 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | U-266 | Lymphoma cancer | IC50 : 55 µM |
| dbacp03737 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | KMM-1 | Skin cancer | IC50 : 57 µM |
| dbacp03738 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | Sudhl-4 | Skin cancer | IC50 : 16 µM |
| dbacp03739 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | Raji | Lymphoma cancer | IC50 : 13 µM |
| dbacp03740 | LfcinB | FKCRRWQWRMKK | Bovine lactoferrin (Lf-B) | Cell membrane disintegration; Regulation of immune response; Apoptosis | MTT/MTS assay | Ramos | Lymphoma cancer | IC50 : 10 µM |
| dbacp04349 | Lytic | KLlLKlLkkLLKlLKKK | Bovine lactoferrin (Lf-B) | Induction of apoptosis | WST-1 assay | KB | Oral cancer | IC50 : 37.4 µMol/L |
| dbacp04701 | mPep1 | RKAFRWAWRMLKKAAPSITCVR | Bovine lactoferrin (Lf-B) | Necrotic cell death by destroying cellular membrane structure; Apoptotic cell death | MTT/MTS assay | HL-60 | Skin cancer | IC50 :8 µM |
| dbacp05038 | P18 | KWKLFKKIPKFLHLAKKF | Bovine lactoferrin (Lf-B) | Necrosis; Cell membrane rupture | MTT/MTS assay | M14 | Skin cancer | 92.2 ± 1.02% cell viability at 10 µM |
| dbacp05245 | pep1 | FKCRRWQWRMKKLGAPSITCVR | Bovine lactoferrin (Lf-B) | Activating an apoptosis-inducing pathway | MTT/MTS assay | HL-60 | Prostate cancer | IC50 :77 µM |
| dbacp06170 | SVS-1 | KVKVKVKVpPTKVKVKVK | Bovine lactoferrin (Lf-B) | Disruption of cell membranes | MTT/MTS assay | KB | Oral cancer | Not found |