22 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp03319 | hP1 | HSHRDFQPVLHLVALNSPLSGGMRG | Human endostatin peptides | Anti-angiogenesis | Matrigel assay | BxPC-3 | Pancreatic cancer | 39% inhibition at 7 mg/kg/d |
| dbacp03320 | hP2 | MRGIRGADFQAFQQARAVGLAGTFR | Human endostatin peptides | Anti-angiogenesis | Matrigel assay | BxPC-3 | Pancreatic cancer | 19% inhibition at 7 mg/kg/d |
| dbacp03321 | hP3 | TFRAFLSSRLQDLYSIVRRADRAAV | Human endostatin peptides | Anti-angiogenesis | Matrigel assay | BxPC-3 | Pancreatic cancer | No inhibition at 7 mg/kg/d |
| dbacp03322 | hP4 | AAVPIVNLKDELLFPSWEALFSGSE | Human endostatin peptides | Anti-angiogenesis | Matrigel assay | BxPC-3 | Pancreatic cancer | No inhibition at 7 mg/kg/d |
| dbacp03323 | hP5 | GSEGPLKPGARIFSFDGKDVLRHPT | Human endostatin peptides | Anti-angiogenesis | Matrigel assay | BxPC-3 | Pancreatic cancer | 29% inhibition at 7 mg/kg/d |
| dbacp03324 | hP6 | HPTWPQKSVWHGSDPNGRRLTESY | Human endostatin peptides | Anti-angiogenesis | Matrigel assay | BxPC-3 | Pancreatic cancer | No inhibition at 7 mg/kg/d |
| dbacp03325 | hP7 | ETWRTEAPSATGQASSLLGGRLLGQ | Human endostatin peptides | Anti-angiogenesis | Matrigel assay | BxPC-3 | Pancreatic cancer | No inhibition at 7 mg/kg/d |
| dbacp03326 | hP8 | LGQSAASAHHAYIVLAIENSFMTASKKK | Human endostatin peptides | Anti-angiogenesis | Matrigel assay | BxPC-3 | Pancreatic cancer | No inhibition at 7 mg/kg/d |
| dbacp03373 | IL-4Rα-lytic hybrid peptide | KQLIRFLKRLDRNGGGKLlLKlLkkLLKlLKKK | Interleukin-4 receptor a (IL-4Ra) chain | Induction of apoptosis | WST-1 assay | BXPC-3 | Pancreatic cancer | IC50 : 6.8 µMol/L |
| dbacp04347 | Lytic | KLlLKlLkkLLKlLKKK | Interleukin-4 receptor a (IL-4Ra) chain | Induction of apoptosis | WST-1 assay | BXPC-3 | Pancreatic cancer | IC50 : 37.1 µMol/L |
| dbacp06206 | TAT-CTMP4 | LDPKLMKEEQMSQAQLFTRSFDDGL | Not found | Inducing apoptosis | Not specified | BxPC-3 | Pancreatic cancer | TAT-CTMP4 induced a dose-dependent increase in apoptosis as detected by %-TUNEL positive cells and %-active caspase-3 (% active caspase-3 ranged from 31.2 to 61.9 at the highest dose tested (10 µM). |
| dbacp06883 | trichoderin A | MDA-P-Cha-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderma sp. fungus, strain 05FI48 | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 = 0.4 μM |
| dbacp06885 | trichoderin A analogue 4 | P-Cha-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderin A | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 = 0.4 μM |
| dbacp06886 | trichoderin A analogue 12 | P-Cha-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderin A | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 > 1 μM |
| dbacp06887 | trichoderin A analogue 13 | P-Cha-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderin A | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 > 1 μM |
| dbacp06888 | trichoderin A analogue 14 | P-Cha-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderin A | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 = 0.6 μM |
| dbacp06889 | trichoderin A analogue 15 | P-Cha-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderin A | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 = 0.5 μM |
| dbacp06890 | trichoderin A analogue 16 | P-Cha-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderin A | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 = 0.4 μM |
| dbacp06891 | trichoderin A analogue 17 | P-Cha-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderin A | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 = 0.4 μM |
| dbacp06892 | trichoderin A analogue 18 | P-Cha-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderin A | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 = 0.2 μM |
| dbacp06902 | trichoderin A analogue 19 | MDA-P-AHMOD-Aib-Aib-IV-Aib-Aib-AMAE | Trichoderin A | Apoptosis inducing | PrestoBlue assay | BxPC-3 | Pancreatic Cancer | IC50 = 0.1 μM |
| dbacp08313 | P1C | YKSIEFC | Synthetic | Not Available | Cell Proliferation assay | BXPC-3 | Pancreatic Cancer | ~40% reduction in cell growth at 20 μM |