89 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01358 | Aurein-3.1 [Cleaved into: Aurein-3.1.1; Aurein-3.1.2] | GLFDIVKKIAGHIAGSI | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | CCRF-CEM | Leukemia | IC50 : 4-5 μM |
| dbacp01989 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 14.7 µg/ml |
| dbacp02047 | Buforin Iib | RAGLQFPVGRLLRRLLRRLLR | Not found | Inducing apoptosis | MTT/MTS assay | CCRF-CEM | Not specified | IC50 : 14.7 µg/ml |
| dbacp02594 | Cyclic [W(RW)4 ]-Dox | WRWRWRWRW | Not found | Inhibition of the cell proliferation | MTT/MTS assay | CCRF-CEM | Leukemia cancer | 62-73% inhibition of cell proliferation at 1 µM |
| dbacp03191 | HAL-1 | GMWSKILGHLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 49 ± 9 µM |
| dbacp03194 | HAL-1/10 | GMWKKILGKLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03197 | HAL-1/12 | GKWSKILGHLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : > 40 µM |
| dbacp03200 | HAL-1/15 | GMWSKLLGHLLR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : > 40 µM |
| dbacp03203 | HAL-1/17 | KMWSKILGHLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03206 | HAL-1/18 | GMWSKILKHLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03209 | HAL-1/19 | GKWKKILGHLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03212 | HAL-1/20 | GKWSKILGKLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : > 40 µM |
| dbacp03215 | HAL-1/21 | GKWKKILGKLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03218 | HAL-1/22 | gmwskilghlir | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03221 | HAL-1/29 | GMWSKILGHLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03224 | HAL-1/4 | GMWSKILGHLKR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03227 | HAL-1/5 | GMWKKILGHLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : > 40 µM |
| dbacp03230 | HAL-1/6 | GMWSKILGHLIK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03233 | HAL-1/9 | GMWSKILGKLIR | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 30 ± 10 µM |
| dbacp03236 | HAL-2 | GKWMSLLKHILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 34 µM |
| dbacp03239 | HAL-2/1 | GKWKSLLKHILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : > 40 µM |
| dbacp03242 | HAL-2/11 | GKWLSLLKHILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03245 | HAL-2/13 | GKWMTLLKHILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03248 | HAL-2/18 | GKWMSLLKHIWK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03251 | HAL-2/19 | GKWMSLLKHWLK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03254 | HAL-2/2 | GKWMKLLKHILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : > 40 µM |
| dbacp03257 | HAL-2/20 | GKWMSLWKHILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03260 | HAL-2/22 | gkwmsllkhilk | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03263 | HAL-2/24 | GKFMSLLKHILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03266 | HAL-2/4 | GKWMSLLKKILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03269 | HAL-2/6 | GKWMSFLKHILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03272 | HAL-2/8 | GKWMSLLKHILK | Sweat bees and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp03682 | Lasioglossin LL-III | VNWKKILGKIIKVVK | Broad-faced Furrow Bee | Cell membrane disintegration | XTT test | CCRF-CEM T | Not found | IC50 : 5.0 μM |
| dbacp03709 | Laxaphycin A | Aoc-Hse-E-Dhb-Hyp-Hse-FLIILG | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-WT | Leukemia cancer | No inhibition at 4 µM |
| dbacp03710 | Laxaphycin A | Aoc-Hse-E-Dhb-Hyp-Hse-FLIILG | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-VLB | Leukemia cancer | No inhibition at 4 µM |
| dbacp03711 | Laxaphycin A | Aoc-Hse-E-Dhb-Hyp-Hse-FLIILG | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-VM1 | Leukemia cancer | No inhibition at 4 µM |
| dbacp03712 | Laxaphycin B | A-Hleu-QN-MeIle-Hasn-TPLT-Ade-V-Hleu | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-WT | Leukemia cancer | 50% inhibition at 1 µM |
| dbacp03713 | Laxaphycin B | A-Hleu-QN-MeIle-Hasn-TPLT-Ade-V-Hleu | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-WT | Leukemia cancer | 44% inhibition at 1 µM |
| dbacp03714 | Laxaphycin B | A-Hleu-QN-MeIle-Hasn-TPLT-Ade-V-Hleu | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-VM1 | Leukemia cancer | 44% inhibition at 1 µM |
| dbacp03715 | Laxaphycin B | A-Hleu-QN-MeIle-Hasn-TPLT-Ade-V-Hleu | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-VLB | Leukemia cancer | 44% inhibition at 1 µM |
| dbacp03716 | Laxaphycin B | A-Hleu-QN-MeIle-Hasn-TPLT-Ade-V-Hleu | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-WT | Leukemia cancer | 40% inhibition at 1 µM |
| dbacp03717 | Laxaphycin B | A-Hleu-QN-MeIle-Hasn-TPLT-Ade-V-Hleu | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-VM1 | Leukemia cancer | 40% inhibition at 1 µM |
| dbacp03718 | Laxaphycin B | A-Hleu-QN-MeIle-Hasn-TPLT-Ade-V-Hleu | Terrestrial blue-green alga or the marine cyanobacterium | Not specified | Cell viability assay | CEM-VLB | Leukemia cancer | 40% inhibition at 1 µM |
| dbacp03749 | LfcinB (Bovine lactoferricin) | FKCRRWQWRM | Not found | Inducing apoptosis | MTT assay | CCRF-CEM | Leukemia | Not found |
| dbacp04103 | linear (RW)4-Dox | RWRWRWRW | Doxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP | Inhibition of the cell proliferation | MTT/MTS assay | CCRF-CEM | Leukemia cancer | 46-69% anti-proliferative activity at 1 µM |
| dbacp04182 | LL-III | VNWKKILGKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 5 ± 3 µM |
| dbacp04185 | LL-III/1 | VNWKKILAKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 3 ± 1 µM |
| dbacp04188 | LL-III/10 | KNWKKILGKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 9 µM |
| dbacp04191 | LL-III/11 | VNWKKIILGKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 4 ± 1 µM |
| dbacp04194 | LL-III/12 | vnwkkilgkiikvvk | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 5 ± 2 µM |
| dbacp04197 | LL-III/15 | VNFKKLLGKLLKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 9 ± 3 µM |
| dbacp04200 | LL-III/16 | VN-NAl-KKLLGKLLKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp04203 | LL-III/17 | VNWRRILGRIIRVVR | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp04206 | LL-III/18 | KNWKKILKKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 7 ± 2 µM |
| dbacp04209 | LL-III/19 | VNWKK-Aib-LGK-Aib-IK-Aib-VK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 8 ± 2 µM |
| dbacp04212 | LL-III/2 | NVWKKILGKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 7 ± 2 µM |
| dbacp04215 | LL-III/22 | KNWKK-Aib-LKK-Aib-IK-Aib-VK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 25 ± 4 µM |
| dbacp04218 | LL-III/23 | VNWKKLLGKLLKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 6 µM |
| dbacp04221 | LL-III/24 | VNWOOILGOIIOVVO | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 5 ± 2 µM |
| dbacp04224 | LL-III/25 | vnwkkllgkllkvvk | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 4 µM |
| dbacp04227 | LL-III/26 | VYWKKILGKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 6 µM |
| dbacp04230 | LL-III/27 | VNWKKVLGKVVKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 18 µM |
| dbacp04233 | LL-III/3 | VNWKKILKKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp04236 | LL-III/34 | NKWKKILGKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 5 ± 3 µM |
| dbacp04239 | LL-III/36 | VNWKKILAKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp04242 | LL-III/37 | VNWKKILGKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 4 ± 1 µM |
| dbacp04245 | LL-III/4 | VNWKKILGKIKKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 18 µM |
| dbacp04248 | LL-III/6 | VNWKKILPKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 6 ± 3 µM |
| dbacp04251 | LL-III/8 | VNWKKILGKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 9 µM |
| dbacp04254 | LL-III/9 | VNWKKILGKIIKVVK | Lasioglossin III and its analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | Not found |
| dbacp04378 | MAC1 | GFGMALKLLKKVL | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 12 ± 6 µM |
| dbacp04381 | MAC1/1 | gfgmalkllkkvl | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 11 µM |
| dbacp04384 | MAC1/10 | GFKMALKLLKKVL | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 16 µM |
| dbacp04387 | MAC1/16 | GFGMALKLLKKVL-NH2 | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 70 µM |
| dbacp04390 | MAC1/19 | GFGMALKLLKKVL-NH2 | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 43 ± 11 µM |
| dbacp04393 | MAC1/2 | AFGMALKLLKKVL | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 17 µM |
| dbacp04396 | MAC1/20 | GFGMALOLLOOVL | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 25 ± 3 µM |
| dbacp04399 | MAC1/21 | GFGMALRLLRRVL | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 22 ± 4 µM |
| dbacp04402 | MAC1/24 | GFGMALKL-(AC6C)-KKVL | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 11 µM |
| dbacp04405 | MAC1/25 | GFGMALK-(AC6C)-LKKVL | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 12 ± 2 µM |
| dbacp04408 | MAC1/26 | GFGMA-(AC6C)-KLLKKVL | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 9 ± 2 µM |
| dbacp04411 | MAC1/3 | LFGMALKLLKKVL | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 22 µM |
| dbacp04414 | MAC1/4 | GFGMALKLLKKVL-NH2 | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 29 µM |
| dbacp04417 | MAC1/6 | GFGMALKLLKKVL-NH2 | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 15 µM |
| dbacp04420 | MAC1/9 | GFKMALKLLKKVL-NH2 | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 14 ± 4 µM |
| dbacp04423 | MAC2 | GTGLPMSERRKIMLMMR | Wallabies and their analogs | Cell membrane damage | MTT/MTS assay | CCRF-CEM | Leukemia cancer | IC50 : 32 µM |
| dbacp04429 | Macropin 1 | GFGMALKLLKKVL | The solitary bee | Cell membrane disintegration | MTT/XTT test | CEM | Not found | IC50 : 12 ± 6 μM |
| dbacp04436 | Macropin 2 | GTGLPMSERRKIMLMMR | The solitary bee | Cell membrane disintegration | MTT/XTT test | CEM | Not found | IC50 : 32 μM |
| dbacp06474 | Varv peptide E (Varv E; Plant defensin) | GLPICGETCVGGTCNTPGCSCSWPVCTRN | Field pansy | Not specified | SRB assay | CEM-SS cells | Not found | IC50 : 3980 nM |