10 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp06645 | Mel-C | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | HeLa | Cervical Cancer | IC50 = 50.72 µg/mL |
| dbacp06646 | Mel-C | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | C-33A | Cervical Cancer | IC50 = 58.63 µg/mL |
| dbacp06647 | Mel-C | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | MCF-7 | Breast Cancer | IC50 = 160.62 µg/mL |
| dbacp06648 | MC–FA | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | HeLa | Cervical Cancer | IC50 = 66.43 µg/mL |
| dbacp06649 | MC–FA | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | C-33A | Cervical Cancer | IC50 = 35.22 µg/ mL |
| dbacp06650 | MC–FA | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | MCF-7 | Breast Cancer | IC50 = 12.63 µg/mL |
| dbacp07339 | D-melittin | gigavlkvlttglpaliswikrkrqqc | Synthetic | pH-triggered release, membrane lysis, immunogenic death | MTS assay | A-549 | Lung Cancer | IC50 = 4.5 µM |
| dbacp07340 | D-melittin | gigavlkvlttglpaliswikrkrqqc | Synthetic | pH-triggered release, membrane lysis, immunogenic death | MTS assay | CT-26 | Colorectal Cancer | IC50 = 2.2 µM |
| dbacp07341 | D-melittin | gigavlkvlttglpaliswikrkrqqc | Synthetic | pH-triggered release, membrane lysis, immunogenic death | MTS assay | MDA-MB-435 WT | Breast Cancer | IC50 = 3.5 µM |
| dbacp07342 | D-melittin | gigavlkvlttglpaliswikrkrqqc | Synthetic | pH-triggered release, membrane lysis, immunogenic death | MTS assay | MDA-MB-435 DOX-R | Breast Cancer | IC50 = 3.4 µM |