dbACP: A Comprehensive Database of Anti-Cancer Peptides

23 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp04476 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane disruption WST-1 assay HeLa Pancreatic cancer IC50 : > 60 µM
dbacp04477 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation LDH leakage assay RT4(G1) Bladder cancer IC50 : 32.3 µM
dbacp04478 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation LDH leakage assay 647V(G2) Bladder cancer IC50 : 54.1 µM
dbacp04479 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation LDH leakage assay 486P(G4) Bladder cancer IC50 : 28.6 µM
dbacp04480 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation WST-1 assay RT4(G1) Bladder cancer IC50 : 484 µM
dbacp04481 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation WST-1 assay 647V(G2) Bladder cancer IC50 : 52.4 µM
dbacp04482 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation WST-1 assay 486P(G4) Bladder cancer IC50 : 57.8 µM
dbacp04483 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation Cell viability assay RT4(G1) Bladder cancer IC50 : 135.3 µM
dbacp04484 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation Cell viability assay 647V(G2) Bladder cancer IC50 : 31 µM
dbacp04485 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation Cell viability assay 486P(G4) Bladder cancer IC50 : 59.4 µM
dbacp04486 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Not specified MTT/MTS assay A-549 Lung cancer IC50 : 110 µM
dbacp04487 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay U-937 Lymphoma cancer IC50 : >150 µg/ml
dbacp04488 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay 8402 Leukemia cancer IC50 : >150 µg/ml
dbacp04489 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay SSKT-1 Hematopoietic cancer IC50 : >150 µg/ml
dbacp04490 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay Daudi Colon cancer IC50 : >150 µg/ml
dbacp04491 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay MLA Leukemia cancer IC50 : >150 µg/ml
dbacp04492 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay Raji Lymphoma cancer IC50 : >150 µg/ml
dbacp04493 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay K-562 Leukemia cancer IC50 : >150 µg/ml
dbacp04494 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay CHP-100 Ewing sarcoma IC50 : >200 µg/ml
dbacp04495 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay MCF-7 Breast cancer IC50 : >200 µg/ml
dbacp04496 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Dissipate ion gradients; Induce osmotic lysis; Membrane damage Trypan blue assay PC-3 Prostate cancer IC50 : >200 µg/ml
dbacp04497 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS Yunnan firebelly toad Membrane perforation Cell viability assay 486P(G4) Bladder cancer IC50 : 59.4 µM
dbacp04498 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS Skin; Stomach, African clawed frog, Africa Membrane disruption Not specified Not found Not found Not found