21 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01250 | Aurein 2.6 | GLFDIAKKVIGVIGSL | Southern bell frog, Australia | Cell membrane penetration | Not specified | Not specified | Not specified | LC50 : 10⁻⁵ to 10⁻⁴ M |
| dbacp01345 | Aurein-2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Membrane disruption | Not specified | Not specified | Not specified | LC50 : 10-5 - 10-4 M |
| dbacp01346 | Aurein-2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Not specified | Not specified | Not found | Not found | Not found |
| dbacp01347 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | RPMI-8226 | Leukemia | IC50 : 4-5 μM |
| dbacp01348 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | EKVX | Lung cancer | IC50 : 5 μM |
| dbacp01349 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | HT29 | Colon cancer | IC50 : 4-5 μM |
| dbacp01350 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | SF-295 | CNS cancer | IC50 : 5 μM |
| dbacp01351 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | SK-MEL-2 | Melanoma | IC50 : 5 μM |
| dbacp01352 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | OVCAR-3 | Ovarian cancer | IC50 : 5 μM |
| dbacp01353 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | RXF 393 | Renal cancer | IC50 : 5 μM |
| dbacp01354 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | DU-145 | Prostate cancer | IC50 : 5 μM |
| dbacp01355 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | MDA-MB-231/ATCC | Breast cancer | IC50 : 5 μM |
| dbacp01423 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Breast tumor cell line | Breast cancer | LC50 : 10 µM |
| dbacp01424 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Leukemia tumor cell line | Leukemia cancer | LC50 : 10-100 µM |
| dbacp01425 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Lung tumor cell line | Lung cancer | LC50 : 10 µM |
| dbacp01426 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Colon tumor cell line | Colon cancer | LC50 : 10-100 µM |
| dbacp01427 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Brain tumor cell line | Brain tumor | LC50 : 10 µM |
| dbacp01428 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Skin tumor cell line | Skin cancer | LC50 : 10 µM |
| dbacp01429 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Ovary tumor cell line | Ovarian cancer | LC50 : 10 µM |
| dbacp01430 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Renal tumor cell line | Renal cancer | LC50 : 10 µM |
| dbacp01431 | Aurein2.6 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disruption | Not specified | Prostate tumor cell line | Prostate cancer | LC50 : 10 µM |