14 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp00979 | Adenoregulin | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV | South American frog, Giant leaf frog | Cell membrane disintegration | LDH leakage assay | PC-3 | Prostate cancer | GI50 : 1.24 ± 0.23 µM |
| dbacp00980 | Adenoregulin | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV | South American frog, Giant leaf frog | Cell membrane disintegration | LDH leakage assay | LNCaP | Prostate cancer | GI50 : 0.31 ± 0.15 µM |
| dbacp00981 | Adenoregulin | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV | South American frog, Giant leaf frog | Cell membrane disintegration | LDH leakage assay | DU-145 | Liver cancer | GI50 : 0.91 ± 0.04 µM |
| dbacp00982 | Adenoregulin | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV | South American frog, Giant leaf frog | Cell membrane disintegration | LDH leakage assay | MDA-MB-231 | Breast cancer | GI50 : 8.06 ± 0.50 µM |
| dbacp00983 | Adenoregulin | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV | South American frog, Giant leaf frog | Cell membrane disintegration | LDH leakage assay | Raji | Lymphoma cancer | GI50 : 2.57 ± 0.75 µM |
| dbacp02655 | Dermaseptin-B2 | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV | Giant leaf frog | Immunomodulatory properties | Cytotoxicity assays, Cell Titer-Glo Luminescent Cell viability assay | A549 | Lung adenocarcinoma | LC50 : < 12 μM |
| dbacp02656 | Dermaseptin-B2 | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV | Giant leaf frog | Immunomodulatory properties | Cytotoxicity assays, Cell Titer-Glo Luminescent Cell viability assay | MDA-MB-231 | Breast adenocarcinoma | LC50 : < 12 μM |
| dbacp02657 | Dermaseptin-B2 | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV | Giant leaf frog | Immunomodulatory properties | Cytotoxicity assays, Cell Titer-Glo Luminescent Cell viability assay | HT-29 | Colorectal adenocarcinoma | LC50 : < 12 μM |
| dbacp02658 | Dermaseptin-B2 | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV | Skin, Giant leaf frog, South America | Selective lysis of cellular membrane | Enzyme immunoassay, Antifungal bioassay | Not found | Not specified | Not found |
| dbacp02659 | Dermaseptin-B3 | ALWKnMLKGIGKLAGQAALGAVKTLVGAE | Giant leaf frog | Membrane lysis | In vitro proliferation assay, Soft agar assay | PC-3 | Human epithelial prostate adenocarcinoma | EC50 : 2 μM |
| dbacp02660 | Dermaseptin-B3 | ALWKnMLKGIGKLAGQAALGAVKTLVGA | South American frog, Giant leaf frog | Apoptosis inducing | Thymidine Incorporation assay | MCF-7 | Breast cancer | Not found |
| dbacp02661 | Dermaseptin-B4 | ALWKDILKNVGKAAGKAVLNTVTDMVNQ | Giant leaf frog | Apoptosis inducing | Thymidine Incorporation assay | MCF-7 | Breast cancer | Not found |
| dbacp02742 | Dermaseptins B2 | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV-NH2 | Giant leaf frog | Interact with the lipids of the plasma membrane | In vitro proliferation assay, Lactate dehydrogenase (LDH)-release assay | PC3 | Human breast cancer | GI50 : 2.17 ± 0.48 μM |
| dbacp02743 | Dermaseptins B2 | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV-NH3 | Giant leaf frog | Interact with the lipids of the plasma membrane | In vitro proliferation assay, Lactate dehydrogenase (LDH)-release assay | U87MG | Human lung cancer | GI50 : >10 μM |