dbACP: A Comprehensive Database of Anti-Cancer Peptides

31 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp06359 TsAP-1 FLSLIPSLVGGSISAFK Venom-derived cDNAlibrary of the Brazilian yellow scorpion Not specified MTT/MTS assay H-838 Lung cancer IC50 : 52.5 µM
dbacp06361 TsAP-2 FLGMIPGLIGGLISAFK Venom-derived cDNAlibrary of the Brazilian yellow scorpion Not specified MTT/MTS assay H-838 Lung cancer IC50 : 11.0 µM
dbacp06369 TsAP-S1 FLSLIPKLVKKIIKAFK Derivative of TsAP-1, Brazilian yellow scorpion venom peptide Not specified MTT/MTS assay H-838 Lung cancer IC50 : 1.6 µM
dbacp06377 TsAP-S2 FLGMIPKLIKKLIKAFK Derivative of TsAP-1, Brazilian yellow scorpion venom peptide Not specified MTT/MTS assay H-838 Lung cancer IC50 : 1.6 µM
dbacp06669 Crabrolin FLPLILRKIVTAL European hornet (Vespa crabro) Not available MTT assay H-838 Lung Cancer IC50 = 27.71 μM
dbacp06674 Crabrolin-4R FLPRILRKIVTAL Synthetic Analog of Crabrolin Not available MTT assay H-838 Lung Cancer IC50 = 11.40 μM
dbacp06679 Crabrolin-4K FLPKILRKIVTAL Synthetic Analog of Crabrolin Not available MTT assay H-838 Lung Cancer IC50 = 22.55 μM
dbacp06684 Crabrolin-TR FLPRILRKIVRAL Synthetic Analog of Crabrolin Not available MTT assay H-838 Lung Cancer IC50 = 4.637 μM
dbacp06689 Crabrolin-FR RLPRILRKIVRAL Synthetic Analog of Crabrolin Not available MTT assay H-838 Lung Cancer IC50 = 31.51 μM
dbacp06694 Crabrolin-AR RLPRILRKIVRRL Synthetic Analog of Crabrolin Not available MTT assay H-838 Lung Cancer IC50 = 41.31 μM
dbacp06699 Crabrolin-PR RLRRILRKIVRRL Synthetic Analog of Crabrolin Not available MTT assay H-838 Lung Cancer IC50 = 32.32 μM
dbacp06723 L14 ALWKSILKNAGKALNEINQIVQ Dermaseptin-SS1- Analog Membrane Permeabilization MTT assay H-838 Lung Cancer IC50 = 64.4 µM
dbacp06725 14V ALWKSILKNAGKAVLNEINQIVQ Dermaseptin-SS1- Analog Membrane Permeabilization MTT assay H-838 Lung Cancer IC50 = 7.0 µM
dbacp06727 14G ALWKSILKNAGKAGLNEINQIVQ Dermaseptin-SS1- Analog Membrane Permeabilization MTT assay H-838 Lung Cancer IC50 = 48.7 µM
dbacp06729 L2V ALWKSILKNVGKVLNEINQIVQ Dermaseptin-SS1- Analog Membrane Permeabilization MTT assay H-838 Lung Cancer IC50 = 2.2 µM
dbacp06731 14V5K ALWKKILKNAGKAVLNEINQIVQ Dermaseptin-SS1- Analog Membrane Permeabilization MTT assay H-838 Lung Cancer IC50 = 8.1 µM
dbacp06733 14VL23 ALWKSILKNAGKAVLNEINQIV Dermaseptin-SS1- Analog Membrane Permeabilization MTT assay H-838 Lung Cancer IC50 = 5.7 µM
dbacp07052 Temporin-PKE FLPLIIGALSSLLPKIF skin secretion of Pelophylax kl. esculentus Charge-optimized membranolysis induces apoptosis. MTT assay H-838 Lung Cancer IC50 = 16.38 μM
dbacp07057 Temporin-PKE-2K FLPLIIGKLSSLLPKIF Synthetic Charge-optimized membranolysis induces apoptosis. MTT assay H-838 Lung Cancer IC50 = 3.07 μM
dbacp07062 Temporin-PKE-K12 FLPLIIGALSSKLPKIF Synthetic Charge-optimized membranolysis induces apoptosis. MTT assay H-838 Lung Cancer IC50 = 22.67 μM
dbacp07067 Temporin-PKE-3K FLPKIIGKLSSLLPKIF Synthetic Charge-optimized membranolysis induces apoptosis. MTT assay H-838 Lung Cancer IC50 = 0.51 μM
dbacp07072 Temporin-PKE-4K FLPKIIGKLSSKLPKIF Synthetic Charge-optimized membranolysis induces apoptosis. MTT assay H-838 Lung Cancer IC50 = 35.28 μM
dbacp07077 Temporin-PKE-i FLPLIIGALSSLLPKiF Synthetic Charge-optimized membranolysis induces apoptosis. MTT assay H-838 Lung Cancer IC50 = 5.28 μM
dbacp07082 Temporin-PKE-3i FLPLiiGALSSLLPKiF Synthetic Charge-optimized membranolysis induces apoptosis. MTT assay H-838 Lung Cancer IC50 = 193.4 μM
dbacp07260 t-DPH1-K4 GLWKKIKNVAAAAGKAALGAL Analogue of t-DPH1 Membrane disruption induces apoptotic signaling. MTT assay H-838 Lung Cancer IC50 = 10.11 μM
dbacp07264 t-DPH1-5K GLWKKIKNVAKAAGKAALGAL Analogue of t-DPH1 Membrane disruption induces apoptotic signaling. MTT assay H-838 Lung Cancer IC50 = 1.796 μM
dbacp07268 t-DPH1-6K GLWKKIKNVAKAAGKAAKGAL Analogue of t-DPH1 Membrane disruption induces apoptotic signaling. MTT assay H-838 Lung Cancer IC50 = 186.1 μM
dbacp07272 t-DPH1-6KW WLWKKIKNVAKAAGKAAKGAL Analogue of t-DPH1 Membrane disruption induces apoptotic signaling. MTT assay H-838 Lung Cancer IC50 = 180.8 μM
dbacp07312 B1OS-L FLPLIASLAGNVVPKIFCKITKRC B-1OS Not Available MTT assay H-838 Lung Cancer IC50 = 3.976 µM
dbacp07317 B1OS-D-L FlPLIASLAGNVVPKIFCKITKRC B-1OS Not Available MTT assay H-838 Lung Cancer IC50 = 2.553 µM
dbacp07927 Phylloseptin-PBa3 FLSLIPHIVSGVAALANHL Phyllomedusa burmeisteri Membrane disruption, apoptosis, selective cytotoxicity MTT assay H-838 Lung Cancer Cell viability ~ 65% at 10-5 M