6 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01008 | Alyteserin-2 | ILGKLLSTAAGLLSNL | Common midwife toad | Cell penetration | Cytotoxicity assay | HT29 | Colorectal adenocarcinoma | LC50 : 28 µM |
| dbacp01349 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | HT29 | Colon cancer | IC50 : 4-5 μM |
| dbacp01965 | Brevinin-2R | KLKNFAKGVAQSLLNKASCKLSGQC | Skin, Marsh frog, Europe | Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death | MTT-assay | HT29/219 | Colon carcinoma | LD50 : 10 – 15 μg/ml |
| dbacp01966 | Brevinin-2R | KLKNFAKGVAQSLLNKASCKLSGQC | Skin, Marsh frog, Europe | Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death | MTT-assay | HT29/219 | Colon carcinoma | LD50 : 20 – 25 μg/ml |
| dbacp01967 | Brevinin-2R | KLKNFAKGVAQSLLNKASCKLSGQC | Skin, Marsh frog, Europe | Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death | MTT-assay | HT29/219 | Colon carcinoma | LD50 : 30 – 40 μg/ml |
| dbacp05916 | Raniseptin PL | GVFDTVKKIGKAVGKFALGVAKNYLNS | Skin secretions, the banana tree dwelling frog, Trinidad, South America | Membrane disruption | Not specified | HT29 | Not found | LC50 : < 30 μM |