dbACP: A Comprehensive Database of Anti-Cancer Peptides

2 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp05013 Omiganan MBI-226 ILRWPWWPWRRK Helical peptide with a predominance of one or more amino acids tryptophane-rich Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis MTT/MTS assay U-937 Lymphoma cancer 27% Cytotoxicity at 0.5 µg/ml
dbacp05489 Pexiganan MSI-78 GIGKFLKKAKKFGKAFVKILKK Helical peptide with a predominance of one or more amino acids tryptophane-rich Disruption of membrane permeability MTT/MTS assay U-937 Lymphoma cancer 75% Cytotoxicity at 0.5 µg/ml