7 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp02112 | cMastoparan-C(cMP-C) | CLNLKALLAVAKKILC | Synthetic construct | Apoptosis | MTT assay | MCF-7 | Human breast cancer | IC50 : 13.66 μM |
| dbacp02742 | Dermaseptins B2 | GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV-NH2 | Giant leaf frog | Interact with the lipids of the plasma membrane | In vitro proliferation assay, Lactate dehydrogenase (LDH)-release assay | PC3 | Human breast cancer | GI50 : 2.17 ± 0.48 μM |
| dbacp03753 | LHRH–BH3 peptide luteinizing hormone-releasing hormone (LHRH) | QHWSYGLRPGMGQVGRQLAIIGDDINRRY | Effectors (BAK, BAX) | Inducing apoptosis | Cytotoxicity assay, MTT assay | MCF-7 | Human breast cancer | Not found |
| dbacp04577 | Mastoparan-C | LNLKALLAVAKKIL | European hornet | Apoptosis | MTT assay | MCF-7 | Human Breast cancer | IC50 : 1.4 μM |
| dbacp05552 | Phylloseptin-PHa | FLSLIPAAISAVSALANHF | Northern orange-legged leaf frog | Disruption of the membrane | MTT assay, Lactate dehydrogenase (LDH) assay | MCF-7 | Human breast cancer | LD50 : < 5 µM |
| dbacp05905 | Ranatuerin-2PLx | GIMDTVKNAAKNLAGQLLDKLKCKITAC | Gram-negative purple non-sulfur bacteria | Inducing apoptosis | MTT Cell viability assay and Lactate dehydrogenase (LDH) leakage assay | MCF-7 | Human breast cancer | IC50 : 20.19 µM |
| dbacp06187 | t Mastoparan-C(tMP-C, Tat (49-57)-Mastoparan-C) | RKKRRQRRRLNLKALLAVAKKIL | Synthetic construct | Apoptosis inducing | MTT assay | MCF-7 | Human breast cancer | IC50 : 3.70 μM |