dbACP: A Comprehensive Database of Anti-Cancer Peptides

10 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp01164 Antimicrobial peptide TsAP-1 MQIKHLITLFFLVLIVADQCSAFLSLIPSLVGGSISAFKGRRKREISAQIEQYKDLQKREAELEELLDRLPMY Brazilian scorpion Membrane disruption MTT Cell viability assay U251 Human glioblastoma IC50 : 0.83 - 2.0 μM
dbacp01944 Brevinin-1H FALGAVTKVLPKLFCLITRKC Hainan Torrent Frog Membrane disruption MTT assay U251MG Human glioblastoma astrocytoma IC50 : 3.37 to 5.87 µM
dbacp02111 cMastoparan-C(cMP-C) CLNLKALLAVAKKILC Synthetic construct Apoptosis MTT assay U251-MG Human glioblastoma astrocytoma IC50 : 8.56 μM
dbacp02723 Dermaseptin-PS1 ALWKTMLKKLGTVALHAGKAALGAVADTISQ Rock Kribensis Cichlid Disrupting cell membranes; Apoptosis Lactate dehydrogenase (LDH) assay, MTT cell proliferation assay U251MG Human glioblastoma MIC : 10−5 M and above
dbacp02778 Disintegrin metalloproteinase/disintegrin echistatin IGIAYNRGMCDPKKSVGTVMDHSTEHLSVAVAMAHEMGHNLGMDHDGNQCNCGGAGCVMSEELIESRSYKFSDCSKNQYQNYLTIYKPQCILNQPLRTDTVSTPVSGNELLQNSANPCYDPLTCHPREGEQCESGPCCRNCKFLKEGTICKRARGDDMDDYCNGKTCDCPRNPHKGPATAKGSVLM Saw-scaled viper Membrane-disruption Transwell migration assay Panc-1 MG human glioblastoma IC50 : 154.5 μM
dbacp02872 Epinecidin-1 H2N-GFIFHIIKGLFHAGKMIHGLV-COOH Orange-spotted grouper Not specified MTS/PMS and trypan blue exclusion assay U87MG Human glioblastoma Not found
dbacp04576 Mastoparan-C LNLKALLAVAKKIL European hornet Apoptosis MTT assay U251-MG Human glioblastoma astrocytoma IC50 : 1.4 μM
dbacp05553 Phylloseptin-PHa FLSLIPAAISAVSALANHF Northern orange-legged leaf frog Disruption of the membrane MTT assay, Lactate dehydrogenase (LDH) assay U251MG Human glioblastoma astrocytoma LD50 : < 5 µM
dbacp05904 Ranatuerin-2PLx GIMDTVKNAAKNLAGQLLDKLKCKITAC Gram-negative purple non-sulfur bacteria Inducing apoptosis MTT Cell viability assay and Lactate dehydrogenase (LDH) leakage assay U251-MG Human glioblastoma astrocytoma IC50 : 16.14 µm
dbacp06186 t Mastoparan-C(tMP-C, Tat (49-57)-Mastoparan-C) RKKRRQRRRLNLKALLAVAKKIL Synthetic construct Apoptosis inducing MTT assay U251-MG Human glioblastoma astrocytoma IC50 : 3.36 μM