6 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01944 | Brevinin-1H | FALGAVTKVLPKLFCLITRKC | Hainan Torrent Frog | Membrane disruption | MTT assay | U251MG | Human glioblastoma astrocytoma | IC50 : 3.37 to 5.87 µM |
| dbacp02111 | cMastoparan-C(cMP-C) | CLNLKALLAVAKKILC | Synthetic construct | Apoptosis | MTT assay | U251-MG | Human glioblastoma astrocytoma | IC50 : 8.56 μM |
| dbacp04576 | Mastoparan-C | LNLKALLAVAKKIL | European hornet | Apoptosis | MTT assay | U251-MG | Human glioblastoma astrocytoma | IC50 : 1.4 μM |
| dbacp05553 | Phylloseptin-PHa | FLSLIPAAISAVSALANHF | Northern orange-legged leaf frog | Disruption of the membrane | MTT assay, Lactate dehydrogenase (LDH) assay | U251MG | Human glioblastoma astrocytoma | LD50 : < 5 µM |
| dbacp05904 | Ranatuerin-2PLx | GIMDTVKNAAKNLAGQLLDKLKCKITAC | Gram-negative purple non-sulfur bacteria | Inducing apoptosis | MTT Cell viability assay and Lactate dehydrogenase (LDH) leakage assay | U251-MG | Human glioblastoma astrocytoma | IC50 : 16.14 µm |
| dbacp06186 | t Mastoparan-C(tMP-C, Tat (49-57)-Mastoparan-C) | RKKRRQRRRLNLKALLAVAKKIL | Synthetic construct | Apoptosis inducing | MTT assay | U251-MG | Human glioblastoma astrocytoma | IC50 : 3.36 μM |