18 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp00824 | AaeAP1 | FLFSLIPSVIAGLVSAIRN | Venom, Aeneas fattailed scorpion, Africa | Membrane lysis | MTT assay | PC-3 | Human prostate carcinoma | MIC : 10−4 to 10−9 M |
| dbacp00832 | AaeAP2 | FLFSLIPSAIAGLVSAIRN | Venom, Aeneas fattailed scorpion, Africa | Membrane lysis | MTT assay | PC-3 | Human prostate carcinoma | MIC : 10−4 to 10−9 M |
| dbacp02110 | cMastoparan-C(cMP-C) | CLNLKALLAVAKKILC | Synthetic construct | Apoptosis | MTT assay | PC-3 | Human prostate carcinoma | IC50 : 13.87 μM |
| dbacp02667 | Dermaseptin-PD-1 | GMWSKIKETAMAAAKEAAKAAGKTISDMIKQ | Skin Secretion, Mexican leaf frog, Mexico, North America | Destroy plasma membrane | MTT assay | PC-3 | Human prostate carcinoma | IC50 : 10-4 and 10-9 M |
| dbacp02670 | Dermaseptin-PD-2 | GMWSKIKNAGKAAAKAAAKAAGKAALDAVSEAI | Skin Secretion, Mexican leaf frog, Mexico, North America | Destroy plasma membrane | MTT assay | PC-3 | Human prostate carcinoma | IC50 : 3.17 μM |
| dbacp02687 | Dermaseptin-PH | ALWKEVLKNAGKAALNEINNLV | Orange-legged leaf frog, Northern orange-legged leaf frog, South America | Cell membrane permeabilization | MTT cell proliferation assay | PC-3 | Human prostate carcinoma | IC50 : 11.8 μM |
| dbacp02726 | Dermaseptin-PS3 | ALWKDILKNAGKAALNEINQIVQ | Skin, the waxy monkey tree frog, South America | Membrane rupture | MTT assay | PC3 | Human prostate carcinoma | IC50 : 18.20 μM |
| dbacp04575 | Mastoparan-C | LNLKALLAVAKKIL | European hornet | Apoptosis | MTT assay | PC-3 | Human prostate carcinoma | IC50 : 1.4 μM |
| dbacp04580 | Mastoparan-Cimals. XXA; UCLL1c) | LNLKALLAVAKKIL | Venom, the European Hornet | Inducing apoptosis | MTT cell viability assay and Lactate dehydrogenase (LDH) leakage assay | PC-3 | Human prostate carcinoma | MIC : 6.26 - 36.65 μM |
| dbacp04586 | Mastoparan-Cimals. XXA; UCLL1c) | LNLKALLAVAKKIL | Venom, the European Hornet | Inducing apoptosis | MTT cell viability assay and Lactate dehydrogenase (LDH) leakage assay | PC-3 | Human prostate carcinoma | IC50 : < 4 μM |
| dbacp05550 | Phylloseptin-PHa | FLSLIPAAISAVSALANHF | Northern orange-legged leaf frog | Disruption of the membrane | MTT assay, Lactate dehydrogenase (LDH) assay | PC-3 | Human prostate carcinoma | LD50 : < 5 µM |
| dbacp05903 | Ranatuerin-2PLx | GIMDTVKNAAKNLAGQLLDKLKCKITAC | Gram-negative purple non-sulfur bacteria | Inducing apoptosis | MTT Cell viability assay and Lactate dehydrogenase (LDH) leakage assay | PC-3 | Human prostate carcinoma | IC50 : 5.79 µM |
| dbacp05908 | Ranatuerin-2PLx | GIMDTVKNAAKNLAGQLLDKLKCSITAC | Skin secretions, the pickerel frog, North America | Inducing apoptosis | MTT Cell viability assay and Lactate dehydrogenase (LDH) leakage assay | PC-3 | Human prostate carcinoma | IC50 : 5.79 µM |
| dbacp06185 | t Mastoparan-C(tMP-C, Tat (49-57)-Mastoparan-C) | RKKRRQRRRLNLKALLAVAKKIL | Synthetic construct | Apoptosis inducing | MTT assay | PC-3 | Human prostate carcinoma | IC50 : 3.86 μM |
| dbacp06276 | Temporin-PE | FLPIVAKLLSGLL | Skin secretions, Common water frog or green frog, Europe | Destabilization of membranes | MTT assay | U251MG | Human prostate carcinoma | TI : 10μM |
| dbacp06277 | Temporin-PE | FLPIVAKLLSGLL | Skin secretions, Common water frog or green frog, Europe | Destabilization of membranes | MTT assay | PC-3 | Human prostate carcinoma | TI : 10μM |
| dbacp06278 | Temporin-PE | FLPIVAKLLSGLL | Skin secretions, Common water frog or green frog, Europe | Destabilization of membranes | MTT assay | MDA-MB-435s | Human prostate carcinoma | TI : 10μM |
| dbacp06285 | Temporin-PE | FLPIVAKLLSGLL | Skin secretions, Common water frog or green frog, Europe | Destabilization of membranes | MTT assay | PC-3 | Human prostate carcinoma | TI : approx. 10μM |