dbACP: A Comprehensive Database of Anti-Cancer Peptides

2 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp07099 K4F6K4 KKKKFFFFFFKKKK Synthetic Positive charge–driven membrane disruption apoptosis CCK-8 assay A-549 Lung Cancer IC50 = 62.64 ± 9.55 μg/mL
dbacp07100 K4F6K4 KKKKFFFFFFKKKK Synthetic Positive charge–driven membrane disruption apoptosis AnnexinV-FITC/PI double staining assay A-549 Lung Cancer apoptotic cells (early and late) increased from 9.59 ± 1.00% to 43.03 ± 2.13%