dbACP: A Comprehensive Database of Anti-Cancer Peptides

43 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp01959 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay Jurkat T-cell Leukemia LD50 : 10 – 15 μg/ml
dbacp01960 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay Jurkat T-cell Leukemia LD50 : 20 – 25 μg/ml
dbacp01961 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay Jurkat T-cell Leukemia LD50 : 30 – 40 μg/ml
dbacp01962 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay BJAB B-cell lymphoma LD50 : 10 – 15 μg/ml
dbacp01963 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay BJAB B-cell lymphoma LD50 : 20 – 25 μg/ml
dbacp01964 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay BJAB B-cell lymphoma LD50 : 30 – 40 μg/ml
dbacp01965 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay HT29/219 Colon carcinoma LD50 : 10 – 15 μg/ml
dbacp01966 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay HT29/219 Colon carcinoma LD50 : 20 – 25 μg/ml
dbacp01967 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay HT29/219 Colon carcinoma LD50 : 30 – 40 μg/ml
dbacp01968 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay SW742 Colon carcinoma LD50 : 10 – 15 μg/ml
dbacp01969 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay SW742 Colon carcinoma LD50 : 20 – 25 μg/ml
dbacp01970 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay SW742 Colon carcinoma LD50 : 30 – 40 μg/ml
dbacp01971 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay L929 Fibrosarcoma LD50 : 10 – 15 μg/ml
dbacp01972 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay L929 Fibrosarcoma LD50 : 20 – 25 μg/ml
dbacp01973 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay L929 Fibrosarcoma LD50 : 30 – 40 μg/ml
dbacp01974 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay MCF-7 Breast adenocarcinoma LD50 : 10 – 15μg/ml
dbacp01975 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay MCF-7 Breast adenocarcinoma LD50 : 20 – 25 μg/ml
dbacp01976 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay MCF-7 Breast adenocarcinoma LD50 : 30 – 40 μg/ml
dbacp01977 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay A549 Lung carcinoma LD50 : 10 – 15 μg/ml
dbacp01978 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay A549 Lung carcinoma LD50 : 20 – 25 μg/ml
dbacp01979 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay A549 Lung carcinoma LD50 : 30 – 40 μg/ml
dbacp01980 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay Jurkat T-cell Leukemia LD50 : 20 – 25 µg/mll
dbacp01981 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay BJAB B-cell lymphoma LD50 : 30 – 40 µg/ml
dbacp01982 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay L929 Fibrosarcoma LD50 : 20 – 25 µg/ml
dbacp01983 Brevinin-2R KLKNFAKGVAQSLLNKASCKLSGQC Skin, Marsh frog, Europe Activates the lysosomal-mitochondrial death pathway; Involves autophagy-like cell death MTT-assay MCF-7 Breast adenocarcinoma LD50 : 10 – 15 µg/ml
dbacp04130 LK1 (Temporin-1CEa Analog peptide) FVDLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MCF-7 Breast cancer IC50 : 20.97 µM
dbacp04131 LK1 (Temporin-1CEa Analog peptide) FVDLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay Bcap-37 Breast cancer IC50 : 18.7 µM
dbacp04132 LK1 (Temporin-1CEa Analog peptide) FVDLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MDA-MB-231 Breast cancer IC50 : 66.4µM
dbacp04133 LK2(5) (Temporin-1CEa Analog peptide) FKDLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MCF-7 Breast cancer IC50 : 44.7 µM
dbacp04134 LK2(5) (Temporin-1CEa Analog peptide) FKDLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay Bcap-37 Breast cancer IC50 : 83.49 µM
dbacp04135 LK2(5) (Temporin-1CEa Analog peptide) FKDLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MDA-MB-231 Breast cancer IC50 : 894.7 µM
dbacp04136 LK2(6) (Temporin-1CEa Analog peptide) FVKLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MCF-7 Breast cancer IC50 : 15.54 µM
dbacp04137 LK2(6) (Temporin-1CEa Analog peptide) FVKLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay Bcap-37 Breast cancer IC50 : 18.9 µM
dbacp04138 LK2(6) (Temporin-1CEa Analog peptide) FVKLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MDA-MB-231 Breast cancer IC50 : 85.41 µM
dbacp04139 LK2(6)A(L) (Temporin-1CEa Analog peptide) FVKLKKILNIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MCF-7 Breast cancer IC50 : 9.01 µM
dbacp04140 LK2(6)A(L) (Temporin-1CEa Analog peptide) FVKLKKILNIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay Bcap-37 Breast cancer IC50 : 10.52 µM
dbacp04141 LK2(6)A(L) (Temporin-1CEa Analog peptide) FVKLKKILNIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MDA-MB-231 Breast cancer IC50 : 34.74 µM
dbacp04142 LK2(6)AN(2L) (Temporin-1CEa Analog peptide) FVKLKKILNIILSIFKK Synthetic construct Cell membrane disintegration MTT-assay MCF-7 Breast cancer IC50 : 11 µM
dbacp04143 LK2(6)AN(2L) (Temporin-1CEa Analog peptide) FVKLKKILNIILSIFKK Synthetic construct Cell membrane disintegration MTT-assay Bcap-37 Breast cancer IC50 : 9.39 µM
dbacp04144 LK2(6)AN(2L) (Temporin-1CEa Analog peptide) FVKLKKILNIILSIFKK Synthetic construct Cell membrane disintegration MTT-assay MDA-MB-231 Breast cancer IC50 : 41.55 µM
dbacp04145 LK3 (Temporin-1CEa Analog peptide) FKKLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MCF-7 Breast cancer IC50 : 27.72 µM
dbacp04146 LK3 (Temporin-1CEa Analog peptide) FKKLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay Bcap-37 Breast cancer IC50 : 25.04 µM
dbacp04147 LK3 (Temporin-1CEa Analog peptide) FKKLKKIANIINSIFKK Synthetic construct Cell membrane disintegration MTT-assay MDA-MB-231 Breast cancer IC50 : 224.8 µM