11 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01190 | Ascaphin-8 | GFKDLLKGAAKALVKTVLF | Coastal Tailed Frog, Pacific Northwest, USA, North America | Membrane disruption and cell lysis | Lactate dehydrogenase assay | HepG2 | Liver | LD50 : 20 µM |
| dbacp02919 | Esculentin-2CHa | GFSSIFRGVAKFASKGLGKDLAKLGVDLVACKISKQC | Chiricahua leopard frog | Membrane disruption and cell lysis | Cytotoxicity assay, Cell TiterGlo Luminescent cell viability assay | A549 cells | Lung adenocarcinoma | LC50 : 10μM |
| dbacp02929 | Figainin 1 | FIGTLIPLALGALTKLFK | Chaco tree frog | Membrane disruption and cell lysis | MTT/MTS assay | NIH/3T3 | Cervical cancer | IC50 : 13 µM |
| dbacp02930 | Figainin 1 | FIGTLIPLALGALTKLFK | Chaco tree frog | Membrane disruption and cell lysis | MTT/MTS assay | B16F10 | Leukemia | IC50 : 10.5 µM |
| dbacp02931 | Figainin 1 | FIGTLIPLALGALTKLFK | Chaco tree frog | Membrane disruption and cell lysis | MTT/MTS assay | MCF | Murine Melanoma | IC50 : 13.7 µM |
| dbacp02932 | Figainin 1 | FIGTLIPLALGALTKLFK | Chaco tree frog | Membrane disruption and cell lysis | MTT/MTS assay | HeLa | Breast cancer | IC50 :11.1 µM |
| dbacp03352 | Hymenochirin-1B | KLSPETKDNLKKVLKGAIKGAIVAKMV | Zaire dwarf clawed frog | Membrane disruption and cell lysis | Cytotoxicity assay, Cell TiterGlo Luminescent Cell viability assay | A549 | Lung cancer | LC50 : 2.5 ± 0.2 μM |
| dbacp03353 | Hymenochirin-1B | KLSPETKDNLKKVLKGAIKGAIVAKMV | Zaire dwarf clawed frog | Membrane disruption and cell lysis | Cytotoxicity assay, Cell TiterGlo Luminescent Cell viability assay | MDA-MB-231 | Breast cancer | LC50 : 9.0 ± 0.3 μM |
| dbacp03354 | Hymenochirin-1B | KLSPETKDNLKKVLKGAIKGAIVAKMV | Zaire dwarf clawed frog | Membrane disruption and cell lysis | Cytotoxicity assay, Cell TiterGlo Luminescent Cell viability assay | HT-29 | Colon cancer | LC50 : 9.7 ± 0.2 μM |
| dbacp03355 | Hymenochirin-1B | KLSPETKDNLKKVLKGAIKGAIVAKMV | Zaire dwarf clawed frog | Membrane disruption and cell lysis | Cytotoxicity assay, Cell TiterGlo Luminescent Cell viability assay | HepG2 | Liver cancer | LC50 : 22.5 ± 1.4 μM |
| dbacp05433 | Peptide XT-7 | GLLGPLLKIAAKVGSNLL | Western clawed frog | Membrane disruption and cell lysis | Lactate dehydrogenase assay | HepG2 | Liver cancer | LD50 : 20 µM |