13 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01987 | Buforin 2 | TRSSRAGLQFPVGRVHRLLRK | Asiatic toad | Disruption of electric potential of the cell membrane; Necrosis, Membranolytic activity leading to apoptosis | MTT/MTS assay | U-937 | Lymphoma cancer | IC50 : 90-95 µg/ml |
| dbacp02105 | Buforin2 | TRSSRAGLQFPVGRVHRLLRK | Asiatic toad | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-937 | Lymphoma cancer | 5% Cytotoxicity at 0.5 µg/ml |
| dbacp02487 | Citropin 1.1 | GLFDVIKKVASVIGGL | Australian blue mountains tree frog | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-938 | Lymphoma cancer | IC50 :40 µg/ml |
| dbacp02512 | Citropin1.1 | GLFDVIKKVASVIGGL | Australian blue mountains tree frog | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-937 | Lymphoma cancer | 60% Cytotoxicity at 0.5 µg/ml |
| dbacp02513 | Citropin1.1 | GLFDVIKKVASVIGGL | Australian blue mountains tree frog | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-937 | Lymphoma cancer | 60% Cytotoxicity at 0.5 µg/ml |
| dbacp02646 | Demegen P-113 | AKRHHGYKRKFH | Thrush | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-939 | Lymphoma cancer | IC50 : 85-90 µg/ml |
| dbacp02647 | Demegen P-113 | AKRHHGYKRKFH | Amphibian skin peptide | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-937 | Lymphoma cancer | 15% Cytotoxicity at 0.5 µg/ml |
| dbacp05012 | Omiganan MBI-226 | ILRWPWWPWRRK | Cattle neutrophils | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-937 | Lymphoma cancer | IC50 : 80 - 85 µg/ml |
| dbacp05013 | Omiganan MBI-226 | ILRWPWWPWRRK | Helical peptide with a predominance of one or more amino acids tryptophane-rich | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-937 | Lymphoma cancer | 27% Cytotoxicity at 0.5 µg/ml |
| dbacp05488 | Pexiganan MSI-78 | GIGKFLKKAKKFGKAFVKILKK | Analog of African clawed frog | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-941 | Lymphoma cancer | IC50 : 20-30 µg/ml |
| dbacp05649 | Protegrin 1 | RGGRLCYCRRRFCVCVGR | Alpha helical peptide without cysteines | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-942 | Lymphoma cancer | IC50 : 30-40 µg/ml |
| dbacp06153 | SSTP1 | FLPLLISALTSLFPKLGK | Skin secretion, the golden frog, the Trivandrum frog, the common wood frog, or the small wood frog, India, Asia | Membranolytic activity | Not specified | Not found | Not found | Not found |
| dbacp06226 | Temporin A | FLPLIGRVLSGIL | Common frog | Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis | MTT/MTS assay | U-943 | Lymphoma cancer | IC50 : 80-90 µg/ml |