22 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp05312 | Peptide 5 | fCYwO-CyLeu-Pen-TKKrPKPfQwFwL-CyLeu-KKLMYPTYLKKfQWAV-Aib-HL | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin | Not specified | MTT/MTS assay | MiaPaCa.2 | Pancreatic cancer | 24.2 % inhibition of cell proliferation at 1 nM |
| dbacp05313 | Peptide 5 | fCYwO-CyLeu-Pen-TKKrPKPfQwFwL-CyLeu-KKLMYPTYLKKfQWAV-Aib-HL | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin | Not specified | MTT/MTS assay | MiaPaCa.2 | Pancreatic cancer | 37.8 % inhibition of cell proliferation at 10 nM |
| dbacp05314 | Peptide 5 | fCYwO-CyLeu-Pen-TKKrPKPfQwFwL-CyLeu-KKLMYPTYLKKfQWAV-Aib-HL | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin | Not specified | MTT/MTS assay | MiaPaCa.2 | Pancreatic cancer | 48.2 % inhibition of cell proliferation at 100 nM |
| dbacp05315 | Peptide 5 | fCYwO-CyLeu-Pen-TKKrPKPfQwFwL-CyLeu-KKLMYPTYLKKfQWAV-Aib-HL | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin | Not specified | MTT/MTS assay | MiaPaCa.2 | Pancreatic cancer | 59.6 % inhibition of cell proliferation at 1 µM |
| dbacp05316 | Peptide 5 | fCYwO-CyLeu-Pen-TKKrPKPfQwFwL-CyLeu-KKLMYPTYLKKfQWAV-Aib-HL | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin | Not specified | MTT/MTS assay | MiaPaCa.2 | Pancreatic cancer | 84.5 % inhibition of cell proliferation at 10 µM |
| dbacp05328 | Peptide 5 | fCYwO-CyLeu-Pen-TKKrPKPfQwFwL-CyLeu-KKLMYPTYLKKfQWAV-Aib-HL | Synthetic peptide of four designed analogs of vasoactive intestinal peptide, bombesin | Not specified | MTT/MTS assay | MiaPaCa.2 | Pancreatic cancer | ED50 : 0.210 µM |
| dbacp05587 | PNC-28 | ETFSDLWKLL | Ant | Membrane disruption | MTT/MTS assay | MiaPaCa.2 | Pancreatic cancer | Cytotoxicity : 80µg/ml |
| dbacp06652 | LUNA18 | Not Available | Synthetic | Not available | CellTiter-Glo Cell Viability assay | MiaPaCa.2 | Pancreatic Cancer | IC50 = 1.4 ± 0.2 nmol/L |
| dbacp07027 | [G10a]-SHa | FLSGIVGMLaKLF | Analog of temporin SHa | Dendrimerization enhances stability, selectivity, anticancer efficacy | Resazurin dye assay | MiaPaCa.2 | Pancreatic Cancer | IC50 = 22.36 ± 6.07 µM |
| dbacp07034 | [G10a]2-SHa | FLSGIVGMLaKLFKFLKaLMFLSGIVG | Analog of temporin SHa | Dendrimerization enhances stability, selectivity, anticancer efficacy | Resazurin dye assay | MiaPaCa.2 | Pancreatic Cancer | IC50 = 8.71 ± 0.35 µM |
| dbacp07041 | [G10a]3-SHa | FLSGIVGMLaKLFFLSGIVGMLaKLFFLSGIVGMLaKLFKK | Analog of temporin SHa | Dendrimerization enhances stability, selectivity, anticancer efficacy | Resazurin dye assay | MiaPaCa.2 | Pancreatic Cancer | IC50 = 6.94 ± 0.27 µM |
| dbacp07047 | Jeff-[G10a]2-SHa | FLSGIVGMLaKLF-jeff-FLSGIVGMLaKLF | Analog of temporin SHa | Dendrimerization enhances stability, selectivity, anticancer efficacy | Resazurin dye assay | MiaPaCa.2 | Pancreatic Cancer | IC50 = 57.45 ± 6.03 µM |
| dbacp08175 | Peptide - 1 | GF(A6c)G(A6c)KK(A6c)G(A6c)F(A6c)G(A6c)GKK(A6c)KKKK | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 = 7.3 µM |
| dbacp08187 | Peptide - 2 | GF(A6c)G(A6c)R(A6c)G(A6c)F(A6c)G(A6c)GR(A6c)RRRR | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 = 5.0 µM |
| dbacp08195 | Peptide - 3 | GF(A6c)G(A6c)Orn(A6c)G(A6c)F(A6c)G(A6c)GOrn(A6c)Orn-Orn- Orn- Orn | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 = 3.6 µM |
| dbacp08203 | Peptide - 4 | GF(A6c)G(A6c)Dab(A6c)G(A6c)F(A6c)G(A6c)GDab(A6c)Dab-Dab-Dab-Dab | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 = 4.4 µM |
| dbacp08211 | Peptide - 6 | GF(A5c)G(A5c)K(A5c)G(A5c)F(A5c)G(A5c)GK(A5c)KKKK | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 > 7.5 µM |
| dbacp08219 | Peptide - 7 | GF(A5c)G(A5c)R(A5c)G(A5c)F(A5c)G(A5c)GR(A5c)RRRR | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 > 7.5 µM |
| dbacp08227 | Peptide - 8 | GF(A6c)G(Tic)K(A6c)G(Tic)F(A6c)G(Tic)GK(Tic)KKKK | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 > 7.5 µM |
| dbacp08235 | Peptide - 9 | GF(A6c)G(Oic)K(A6c)G(Oic)F(A6c)G(Oic)GK(Oic)KKKK | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 > 7.5 µM |
| dbacp08243 | Peptide - 10 | GF(A5c)G(A6c)K(A5c)G(A6c)F(A5c)G(A6c)GK(A5c)KKKK | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 > 7.5 µM |
| dbacp08251 | Peptide - 11 | KKKKGF(A6c)G(A6c)K(A6c)G(A6c)F(A6c)G(A6c)GK(A6c) | Synthetic | Not Available | CellTiter-Glo assay | MiaPaCa.2 | Pancreatic Cancer | IC50 > 7.5 µM |