11 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp03517 | Kassiniatuerin-3 | FIQHLIPLIPHAIQGIKDIF | Senegal running frog, Africa | Membranolytic mechanism | MTT assay | NCI-H157 | Non-small cell Lung cancer | IC50 : 21.54 µM |
| dbacp05547 | Phylloseptin-PHa | FLSLIPAAISAVSALANHF | Skin secretions, Orange-legged Leaf Frog, South America | Membrane disruption | MTT cell viability assay | NCI-H157 | Lung cancer | IC50 : 14.10 μM |
| dbacp05549 | Phylloseptin-PHa | FLSLIPAAISAVSALANHF | Northern orange-legged leaf frog | Disruption of the membrane | MTT assay, Lactate dehydrogenase (LDH) assay | NCI-H157 | Non-small-cell Lung cancer | LD50 : < 5 µM |
| dbacp05554 | Phylloseptin-PTa | FLSLIPKIAGGIAALAKHL | Skin secretions, the Brown-bellied Leaf Frog, South America | Membrane disruption | MTT Cell viability assay | NCI-H157 | Lung cancer | IC50 : 6.73 μM |
| dbacp06267 | Temporin-PE | FLPIVAKLLSGLL | Skin secretions, Common water frog or green frog, Europe | Destabilization of membranes | MTT assay | NCI-H157 | Lung cancer | TI : 10μM |
| dbacp06271 | Temporin-PE | FLPIVAKLLSGLL | Skin secretions, Common water frog or green frog, Europe | Destabilization of membranes | MTT assay | NCI-H157 | Human neuronal glioblastoma | TI : 10μM |
| dbacp06275 | Temporin-PE | FLPIVAKLLSGLL | Skin secretions, Common water frog or green frog, Europe | Destabilization of membranes | MTT assay | NCI-H157 | Human neuronal glioblastoma | TI : 10μM |
| dbacp06279 | Temporin-PE | FLPIVAKLLSGLL | Skin secretions, Common water frog or green frog, Europe | Destabilization of membranes | MTT assay | NCI-H157 | Melanoma | TI : 10μM |
| dbacp06283 | Temporin-PE | FLPIVAKLLSGLL | Skin secretions, Common water frog or green frog, Europe | Destabilization of membranes | MTT assay | NCI-H157 | Lung cancer | TI : approx. 10μM |
| dbacp06366 | TsAP-2 | FLGMIPGLIGGLISAFK | Venom, the Brazilian yellow scorpion, South America | Not specified | MTT/MTS assay | NCI-H157 | Human squamous carcinoma | IC50 : 4.1 µM |
| dbacp06374 | TsAP-S1 | FLSLIPKLVKKIIKAFK | The iNot foundctive natural peptide TsAP-1 was made active by increasing 4 lysines and one leucine, template-based design | Not specified | MTT/MTS assay | NCI-H157 | Human squamous carcinoma | IC50 : 55.9 µM |