dbACP: A Comprehensive Database of Anti-Cancer Peptides

2 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp05649 Protegrin 1 RGGRLCYCRRRFCVCVGR Alpha helical peptide without cysteines Disruption of electric potential of the cell membrane; Necrosis; Membranolytic activity leading to apoptosis MTT/MTS assay U-942 Lymphoma cancer IC50 : 30-40 µg/ml
dbacp05650 Protegrin 1 RGGRLCYCRRRFCVCVGR Alpha helical peptide without cysteines Not specified MTT/MTS assay U-937 Lymphoma cancer 61% Cytotoxicity at 0.5 µg/ml