4 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01386 | Aurein-3.3 [Cleaved into: Aurein-3.3.1] | GLFDIVKKIAGHIVSSI | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | SF-268 | CNS cancer | IC50 : 5 μM |
| dbacp02012 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | SF-268 | Brain tumor | IC50 : 12.4 µg/ml |
| dbacp02070 | Buforin Iib | RAGLQFPVGRLLRRLLRRLLR | Not found | Inducing apoptosis | MTT/MTS assay | SF-268 | Not specified | IC50 : 12.4 µg/ml |
| dbacp07256 | ATX-101 | MDRWLVKWKKKRKIRRRRRRRRRRR | Synthetic | PCNA interference disrupts DNA repair. | CCK-8 assay | SF-268 | Brain Tumor | IC50 = 4.8 ± 0.1 μM |