14 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp01351 | Aurein-2.7 | GLFDIAKKVIGVIGSL | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | SK-MEL-2 | Melanoma | IC50 : 5 μM |
| dbacp01387 | Aurein-3.3 [Cleaved into: Aurein-3.3.1] | GLFDIVKKIAGHIVSSI | Southern bell frog | Cell membrane disintegration | One-dose and five-dose assay | SK-MEL-28 | Melanoma | IC50 : 5 μM |
| dbacp02021 | Buforin IIb | RAGLQFPVGRLLRRLLRRLLR | Histone H2A | Inducing mitochondria-dependent apoptosis | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 11.1 µg/ml |
| dbacp02079 | Buforin Iib | RAGLQFPVGRLLRRLLRRLLR | Not found | Inducing apoptosis | MTT/MTS assay | SK-MEL-2 | Not specified | IC50 : 11.1 µg/ml |
| dbacp02977 | GA-K3 | FLGWLFKWAKK | Undecapeptide analogues derived from Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 27.39 µM |
| dbacp02984 | GA-K3 | FLGWLFKWAKK | Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 27.39 µM |
| dbacp02991 | GA-K4 | FLKWLFKWAKK | Undecapeptide analogues derived from Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 :22.25 µM |
| dbacp02998 | GA-K4 | FLKWLFKWAKK | Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 22.25 µM |
| dbacp03005 | GA-W3 | FLGWLFKWAWK | Undecapeptide analogues derived from Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 13.97 µM |
| dbacp03012 | GA-W3 | FLGWLFKWAWK | Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 13.97 µM |
| dbacp03019 | GA-W4 | FLWWLFKWAWK | Undecapeptide analogues derived from Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 13.16 µM |
| dbacp03026 | GA-W4 | FLWWLFKWAWK | Brevinin-1EMa | Cell membrane disruption | MTT/MTS assay | SK-MEL-2 | Skin cancer | IC50 : 13.16 µM |
| dbacp07014 | Sansalvimide A | LXVLF | Fusarium sp. | Not Available | Not Available | SK-MEL-2 | Skin Cancer | IC50 = 5.9 µg/ml |
| dbacp07322 | PCC-1 | KKRKKKAFALKFVVDLI | Poecilocoris lewisi | Sp1 suppression, apoptosis, cell-cycle arrest | MTS assay | SK-Mel-28 | Skin Cancer | IC50 = 50.8 µM |