dbACP: A Comprehensive Database of Anti-Cancer Peptides

20 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp00718 2XAkt-in VTDHPDRLWAWEKGGGVTDHPDRLWAWEK Not found Inducing apoptosis Cell death assay T4 Leukemia Not found
dbacp00992 Akt-in AVTDHPDRLWAWEKF Not found Inducing apoptosis Co-immunoprecipitation, GST Pull-down,GST Competition, In Vitro Akt Kinase, PKA Kinase, In Vitro PDK1 Kinase, PtdIns(3,4,5)P3 Lipid-Protein Pull-down, Proliferation assay, Cell Death assay and Mitochondrial Permeability Transition assay T4 T-cell Leukemia Not found
dbacp02050 Buforin Iib RAGLQFPVGRLLRRLLRRLLR Not found Inducing apoptosis MTT/MTS assay MOLT4 Not specified IC50 : 17.0 µg/ml
dbacp02327 Cecropin A KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK Silkmoth Membrane disruption WST-1 assay RT4 Bladder cancer IC50 : 231.26 µg/ml
dbacp02331 Cecropin A KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK Silkmoth Membrane disruption Cell viability assay RT4 Bladder cancer IC50 : 96.22 µg/ml
dbacp02335 Cecropin A KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK Silkmoth Membrane disruption LDH leakage assay RT4 Bladder cancer IC50 : 289.3 µg/ml
dbacp02346 Cecropin B KWKIFKKIEKVGRNIRNGIIKAGPAVAVLGEAKAL Chinese oak silk moth Membrane disruption WST-1 assay RT4 Bladder cancer IC50 : 184.81 µg/ml
dbacp02350 Cecropin B KWKIFKKIEKVGRNIRNGIIKAGPAVAVLGEAKAL Chinese oak silk moth Membrane disruption Cell viability assay RT4 Bladder cancer IC50 : 92.9 µg/ml
dbacp02354 Cecropin B KWKIFKKIEKVGRNIRNGIIKAGPAVAVLGEAKAL Chinese oak silk moth Membrane disruption LDH leakage assay RT4 Bladder cancer IC50 : 240.4 µg/ml
dbacp04293 Lt-MAP2 LIKKLKEYLKKLI Derivatives of Latarcin-3a Not specified Not specified MOLT4 Not found Not found
dbacp04477 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation LDH leakage assay RT4(G1) Bladder cancer IC50 : 32.3 µM
dbacp04480 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation WST-1 assay RT4(G1) Bladder cancer IC50 : 484 µM
dbacp04483 Magainin 2 GIGKFLHSAKKFGKAFVGEIMNS African clawed frog Membrane perforation Cell viability assay RT4(G1) Bladder cancer IC50 : 135.3 µM
dbacp05056 P2 RALGWSCL Plant sources Inducing apoptosis MTS assay MOLT4 Not specified IC50 : 700 μg/mL
dbacp05464 Peptidoglycan recognition protein 1 MSRRSMLLAWALPSLLRLGAAQETEDPACCSPIVPRNEWKALASECAQHLSLPLRYVVVSHTAGSSCNTPASCQQQARNVQHYHMKTLGWCDVGYNFLIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMDRVPTPQAIRAAQGLLACGVAQGALRSNYVLKGHRDVQRTLSPGNQLYHLIQNWPHYRSP Human Apoptosis inducing; Necrotic cell death Enzyme inhibition assay Molt4 Not specified Not found
dbacp05588 Polyarginine (R11) RRRRRRRRRRR Not found Not specified Not specified T24, 5637, RT4 Bladder cancer Not found
dbacp05918 Raniseptin-3 AWLDKLKSIGKVVGKVAIGVAKNLLNPQ Skin secretion, Chaco tree frog, South America Disrupting cancer cell membranes MTT and LDH assay NIH3T4 Murine melanoma IC50 : 4.21 μM
dbacp06415 U3 NGSIPATWASL Date palm Cell proliferation inhibition MTT/MTS assay T47D Breast cancer IC50 : 434.7 – 616.5 μM
dbacp06418 U7 NCSIHGDIPAY Date palm Cell proliferation inhibition MTT/MTS assay T47D Breast cancer IC50 : 485.3–702.8 μM
dbacp06532 VS-9 VKLRSLLCS Plant sources Inducing apoptosis MTT assay MOLT4 Leukemia Not found