7 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp04283 | Lovastatin nonaketide synthase | MAQSMYPNEPIVVVGSGCRFPGDANTPSKLWELLQHPRDVQSRIPKERFDVDTFYHPDGKHHGRTNAPYAYVLQDDLGAFDAAFFNIQAGEAESMDPQHRLLLETVYEAVTNAGMRIQDLQGTSTAVYVGVMTHDYETVSTRDLESIPTYSATGVAVSVASNRISYFFDWHGPSMTIDTACSSSLVAVHLAVQQLRTGQSSMAIAAGANLILGPMTFVLESKLSMLSPSGRSRMWDAGADGYARGEAVCSVVLKTLSQALRDGDTIECVIRETGVNQDGRTTGITMPNHSAQEALIKATYAQAGLDITKAEDRCQFFEAHGTGTPAGDPQEAEAIATAFFGHEQVARSDGNERAPLFVGSAKTVVGHTEGTAGLAGLMKASFAVRHGVIPPNLLFDKISPRVAPFYKNLRIPTEATQWPALPPGQPRRASVNSFGFGGTNAHAIIEEYMEPEQNQLRVSNNEDCPPMTGVLSLPLVLSAKSQRSLKIMMEEMLQFLQSHPEIHLHDLTWSLLRKRSVLPFRRAIVGHSHETIRRALEDAIEDGIVSSDFTTEVRGQPSVLGIFTGQGAQWPGMLKNLIEASPYVRNIVRELDDSLQSLPEKYRPSWTLLDQFMLEGEASNVQYATFSQPLCCAVQIVLVRLLEAARIRFTAVVGHSSGEIACAFAAGLISASLAIRIAYLRGVVSAGGARGTPGAMLAAGMSFEEAQEICELDAFEGRICVAASNSPDSVTFSGDANAIDHLKGMLEDESTFARLLKVDTAYHSHHMLPCADPYMQALEECGCAVADAGSPAGSVPWYSSVDAENRQMAARDVTAKYWKDNLVSPVLFSHAVQRAVVTHKALDIGIEVGCHPALKSPCVATIKDVLSGVDLAYTGCLERGKNDLDSFSRALAYLWERFGASSFDADEFMRAVAPDRPCMSVSKLLPAYPWDRSRRYWVESRATRHHLRGPKPHLLLGKLSEYSTPLSFQWLNFVRPRDIEWLDGHALQGQTVFPAAGYIVMAMEAALMIAGTHAKQVKLLEILDMSIDKAVIFDDEDSLVELNLTADVSRNAGEAGSMTISFKIDSCLSKEGNLSLSAKGQLALTIEDVNPRTTSASDQHHLPPPEEEHPHMNRVNINAFYHELGLMGYNYSKDFRRLHnMQRADLRASGTLDFIPLMDEGNGCPLLLHPASLDVAFQTVIGAYSSPGDRRLRCLYVPTHVDRITLVPSLCLATAESGCEKVAFNTINTYDKGDYLSGDIVVFDAEQTTLFQVENITFKPFSPPDASTDHAMFARWSWGPLTPDSLLDNPEYWATAQDKEAIPIIERIVYFYIRSFLSQLTLEERQQAAFHLQKQIEWLEQVLASAKEGRHLWYDPGWENDTEAQIEHLCTANSYHPHVRLVQRVGQHLLPTVRSNGNPFDLLDHDGLLTEFYTNTLSFGPALHYARELVAQIAHRYQSMDILEIGAGTGGATKYVLATPQLGFNSYTYTDISTGFFEQAREQFAPFEDRMVFEPLDIRRSPAEQGFEPHAYDLIIASNVLHATPDLEKTMAHARSLLKPGGQMVILEITHKEHTRLGFIFGLFADWWAGVDDGRCTEPFVSFDRWDAILKRVGFSGVDSRTTDRDANLFPTSVFSTHAIDATVEYLDAPLASSGTVKDSYPPLVVVGGQTPQSQRLLNDIKAIMPPRPLQTYKRLVDLLDAEELPMKSTFVMLTELDEELFAGLTEETFEATKLLLTYASNTVWLTENAWVQHPHQASTIGMLRSIRREHPDLGVHVLDVDAVETFDATFLVEQVLRLEEHTDELASSTTWTQEPEVSWCKGRPWIPRLKRDLARNNRMNSSRRPIYEMIDSSRAPVALQTARDSSSYFLESAETWFVPESVQQMETKTIYVHFSCPHALRVGQLGFFYLVQGHVQEGNREVPVVALAERNASIVHVRPDYIYTEADNNLSEGGGSLMVTVLAAAVLAETVISTAKCLGVTDSILVLNPPSICGQMLLHAGEEIGLQVHLATTSGNRSSVSAGDAKSWLTLHARDTDWHLRRVLPRGVQALVDLSADQSCEGLTQRMMKVLMPGCAHYRAADLFTDTVSTELHSGSRHQASLPAAYWEHVVSLARQGLPSVSEGWEVMPCTQFAAHADKTRPDLSTVISWPRESDEATLPTRVRSIDAETLFAADKTYLLVGLTGDLGRSLGRWMVQHGACHIVLTSRNPQVNPKWLAHVEELGGRVTVLSMDVTSQNSVEAGLAKLKDLHLPPVGGIAFGPLVLQDVMLNnMELPMMEMVLNPKVEGVRILHEKFSDPTSSNPLDFFVMFSSIVAVMGNPGQANYSAANCYLQALAQQRVASGLAASTIDIGAVYGVGFVTRAELEEDFNAIRFMFDSVEEHELHTLFAEAVVAGRRAVHQQEQQRKFATVLDMADLELTTGIPPLDPALKDRITFFDDPRIGNLKIPEYRGAKAGEGAAGSKGSVKEQLLQATNLDQVRQIVIDGLSAKLQVTLQIPDGESVHPTIPLIDQGVDSLGAVTVGTWFSKQLYLDLPLLKVLGGASITDLANEAAARLPPSSIPLVAATDGGAESTDNTSENEVSGREDTDLSAAATITEPSSADEDDTEPGDEDVPRSHHPLSLGQEYSWRIQQGAEDPTVFNNTIGMFMKGSIDLKRLYKALRAVLRRHEIFRTGFANVDENGMAQLVFGQTKNKVQTIQVSDRAGAEEGYRQLVQTRYNPAAGDTLRLVDFFWGQDDHLLVVAYHRLVGDGSTTENIFVEAGQLYDGTSLSPHVPQFADLAARQRAMLEDGRMEEDLAYWKKMHYRPSSIPVLPLMRPLVGNSSRSDTPNFQHCGPWQQHEAVARLDPMVAFRIKERSRKHKATPMQFYLAAYQVLLARLTDSTDLTVGLADTNRATVDEMAAMGFFANLLPLRFRDFRPHITFGEHLIATRDLVREALQHARVPYGVLLDQLGLEVPVPTSNQPAPLFQAVFDYKQGQAESGTIGGAKITEVIATRERTPYDVVLEMSDDPTKDPLLTAKLQSSRYEAHHPQAFLESYMSLLSMFSMNPALKLA | Soil mold | Induce G1 arrest and increased apoptotic cell populations at the sub-G1 phase | MTT assay | SW1736 | Human anaplastic thyroid cancer | MIC : 0 – 20 µM |
| dbacp04284 | Lovastatin nonaketide synthase | MAQSMYPNEPIVVVGSGCRFPGDANTPSKLWELLQHPRDVQSRIPKERFDVDTFYHPDGKHHGRTNAPYAYVLQDDLGAFDAAFFNIQAGEAESMDPQHRLLLETVYEAVTNAGMRIQDLQGTSTAVYVGVMTHDYETVSTRDLESIPTYSATGVAVSVASNRISYFFDWHGPSMTIDTACSSSLVAVHLAVQQLRTGQSSMAIAAGANLILGPMTFVLESKLSMLSPSGRSRMWDAGADGYARGEAVCSVVLKTLSQALRDGDTIECVIRETGVNQDGRTTGITMPNHSAQEALIKATYAQAGLDITKAEDRCQFFEAHGTGTPAGDPQEAEAIATAFFGHEQVARSDGNERAPLFVGSAKTVVGHTEGTAGLAGLMKASFAVRHGVIPPNLLFDKISPRVAPFYKNLRIPTEATQWPALPPGQPRRASVNSFGFGGTNAHAIIEEYMEPEQNQLRVSNNEDCPPMTGVLSLPLVLSAKSQRSLKIMMEEMLQFLQSHPEIHLHDLTWSLLRKRSVLPFRRAIVGHSHETIRRALEDAIEDGIVSSDFTTEVRGQPSVLGIFTGQGAQWPGMLKNLIEASPYVRNIVRELDDSLQSLPEKYRPSWTLLDQFMLEGEASNVQYATFSQPLCCAVQIVLVRLLEAARIRFTAVVGHSSGEIACAFAAGLISASLAIRIAYLRGVVSAGGARGTPGAMLAAGMSFEEAQEICELDAFEGRICVAASNSPDSVTFSGDANAIDHLKGMLEDESTFARLLKVDTAYHSHHMLPCADPYMQALEECGCAVADAGSPAGSVPWYSSVDAENRQMAARDVTAKYWKDNLVSPVLFSHAVQRAVVTHKALDIGIEVGCHPALKSPCVATIKDVLSGVDLAYTGCLERGKNDLDSFSRALAYLWERFGASSFDADEFMRAVAPDRPCMSVSKLLPAYPWDRSRRYWVESRATRHHLRGPKPHLLLGKLSEYSTPLSFQWLNFVRPRDIEWLDGHALQGQTVFPAAGYIVMAMEAALMIAGTHAKQVKLLEILDMSIDKAVIFDDEDSLVELNLTADVSRNAGEAGSMTISFKIDSCLSKEGNLSLSAKGQLALTIEDVNPRTTSASDQHHLPPPEEEHPHMNRVNINAFYHELGLMGYNYSKDFRRLHnMQRADLRASGTLDFIPLMDEGNGCPLLLHPASLDVAFQTVIGAYSSPGDRRLRCLYVPTHVDRITLVPSLCLATAESGCEKVAFNTINTYDKGDYLSGDIVVFDAEQTTLFQVENITFKPFSPPDASTDHAMFARWSWGPLTPDSLLDNPEYWATAQDKEAIPIIERIVYFYIRSFLSQLTLEERQQAAFHLQKQIEWLEQVLASAKEGRHLWYDPGWENDTEAQIEHLCTANSYHPHVRLVQRVGQHLLPTVRSNGNPFDLLDHDGLLTEFYTNTLSFGPALHYARELVAQIAHRYQSMDILEIGAGTGGATKYVLATPQLGFNSYTYTDISTGFFEQAREQFAPFEDRMVFEPLDIRRSPAEQGFEPHAYDLIIASNVLHATPDLEKTMAHARSLLKPGGQMVILEITHKEHTRLGFIFGLFADWWAGVDDGRCTEPFVSFDRWDAILKRVGFSGVDSRTTDRDANLFPTSVFSTHAIDATVEYLDAPLASSGTVKDSYPPLVVVGGQTPQSQRLLNDIKAIMPPRPLQTYKRLVDLLDAEELPMKSTFVMLTELDEELFAGLTEETFEATKLLLTYASNTVWLTENAWVQHPHQASTIGMLRSIRREHPDLGVHVLDVDAVETFDATFLVEQVLRLEEHTDELASSTTWTQEPEVSWCKGRPWIPRLKRDLARNNRMNSSRRPIYEMIDSSRAPVALQTARDSSSYFLESAETWFVPESVQQMETKTIYVHFSCPHALRVGQLGFFYLVQGHVQEGNREVPVVALAERNASIVHVRPDYIYTEADNNLSEGGGSLMVTVLAAAVLAETVISTAKCLGVTDSILVLNPPSICGQMLLHAGEEIGLQVHLATTSGNRSSVSAGDAKSWLTLHARDTDWHLRRVLPRGVQALVDLSADQSCEGLTQRMMKVLMPGCAHYRAADLFTDTVSTELHSGSRHQASLPAAYWEHVVSLARQGLPSVSEGWEVMPCTQFAAHADKTRPDLSTVISWPRESDEATLPTRVRSIDAETLFAADKTYLLVGLTGDLGRSLGRWMVQHGACHIVLTSRNPQVNPKWLAHVEELGGRVTVLSMDVTSQNSVEAGLAKLKDLHLPPVGGIAFGPLVLQDVMLNnMELPMMEMVLNPKVEGVRILHEKFSDPTSSNPLDFFVMFSSIVAVMGNPGQANYSAANCYLQALAQQRVASGLAASTIDIGAVYGVGFVTRAELEEDFNAIRFMFDSVEEHELHTLFAEAVVAGRRAVHQQEQQRKFATVLDMADLELTTGIPPLDPALKDRITFFDDPRIGNLKIPEYRGAKAGEGAAGSKGSVKEQLLQATNLDQVRQIVIDGLSAKLQVTLQIPDGESVHPTIPLIDQGVDSLGAVTVGTWFSKQLYLDLPLLKVLGGASITDLANEAAARLPPSSIPLVAATDGGAESTDNTSENEVSGREDTDLSAAATITEPSSADEDDTEPGDEDVPRSHHPLSLGQEYSWRIQQGAEDPTVFNNTIGMFMKGSIDLKRLYKALRAVLRRHEIFRTGFANVDENGMAQLVFGQTKNKVQTIQVSDRAGAEEGYRQLVQTRYNPAAGDTLRLVDFFWGQDDHLLVVAYHRLVGDGSTTENIFVEAGQLYDGTSLSPHVPQFADLAARQRAMLEDGRMEEDLAYWKKMHYRPSSIPVLPLMRPLVGNSSRSDTPNFQHCGPWQQHEAVARLDPMVAFRIKERSRKHKATPMQFYLAAYQVLLARLTDSTDLTVGLADTNRATVDEMAAMGFFANLLPLRFRDFRPHITFGEHLIATRDLVREALQHARVPYGVLLDQLGLEVPVPTSNQPAPLFQAVFDYKQGQAESGTIGGAKITEVIATRERTPYDVVLEMSDDPTKDPLLTAKLQSSRYEAHHPQAFLESYMSLLSMFSMNPALKLA | Soil mold | Induce G1 arrest and increased apoptotic cell populations at the sub-G1 phase | MTT assay | 8305C | Human anaplastic thyroid cancer | MIC : 0 – 20 µM |
| dbacp04285 | Lovastatin nonaketide synthase, polyketide synthase component | MAQSMYPNEPIVVVGSGCRFPGDANTPSKLWELLQHPRDVQSRIPKERFDVDTFYHPDGKHHGRTNAPYAYVLQDDLGAFDAAFFNIQAGEAESMDPQHRLLLETVYEAVTNAGMRIQDLQGTSTAVYVGVMTHDYETVSTRDLENIPTYSATGVAVSVASNRISYFFDWHGPSMTIDTACSSSLVAVHLAVQQLRTGQSSMAIAAGANLILGPMTFVLESKLSMLSPSGRSRMWDAGADGYARGEAVCSVVLKTLSQALRDGDTIECVIRETGVNQDGRTTGITMPNHSAQEALIKATYAQAGLDITKAEDRCQFFEAHGTGTPAGDPQEAEAIATAFFGHEQVARSDGNERAPLFVGSAKTVVGHTEGTAGLAGLMKASFAVRHGVIPPNLLFDKISPRVAPFYKNLRIPTEATQWPALPPGQPRRASVNSFGFGGTNAHAIIEEYMEPEQNQLRVSNNEDCPPMTGVLSLPLVLSAKSQRSLKIMMEEMLQFLETHPEIHLHDLTWSLLRKRSVLPFRRAIVGHSHETIRRALEDAIEDGIVSSDFTTEVRGQPSVLGIFTGQGAQWPGMLKNLIEASPYVRSIVRELDDSLQSLPEKYRPSWTLLDQFMLEGEASNVQYASFSQPLCCAVQIVLVRLLEAARIRFTAVVGHSSGEIACAFAAGLISASVAIRIAYLRGVVSAGGARGTPGAMLAAGMSFEEAQEICELDAFEGRICVAASNSPDSVTFSGDANAIDHLKSMLEDESTFARLLRVDTAYHSHHMLPCADPYMQALEECGCAVADAGSPAGSVPWYSSVNAENRQMAARDVTAEYWKDNLVSPVLFSHAVQRAVVTHKALDIGIEVGCHPALKSPCVATIKDVLSGVDLAYTGCLERGKNDLDTFSRALAYLWERFGASSFDADEFMRAVAPDRPCMSVSKLLPAYPWDHSRRYWVESRATRHHLRGPKPHLLLGKLSEYSTPLSFQWLNFVRPRDIEWLDGHALQGQTVFPAAGYIVMAMEAALMIAGTHAKQVQLLEILDMSIDKAVIFDDEDSLVELNLTADVSRNAGEAGSMTISFKIDSCLSKEGNLSLSAKGQLALMIGDVNSRTTSASDQHHLPPPEEEHPHMNRVNIKAFYHELGLMGYNYSKDFRRLHnMQRADLRASGTIDFIPLMDEGNGCPLLLHPASLDVAFQTVIGAYSSPGDRRLRCLYVPTHVDRITLVPSLCLATAESGCEKVAFNTINTYDKGDYLSGDIAVFDAEQTTLFQVENITFKPFSPPDASTDHAMFARWSWGPLTPDSLLDNPEYWATAQDKEAIPIIERIVYFYIRSFLNQLTLEERQKAAFHLQKQIEWLEQVLASAKEGRHLWYDPGWENDTEAQIEHLCTANSYHPHVRLVQRVGQHLLPTVRSNGNPFDLLDHDGLLTEFYTNTLSFGPALHYARELVAQIAHRYQSMDILEIGAGTGGATKYVLATPQLGFNSYTYTDISTGFFEQAREQFAPFEDRMVFEPLDIRRSPAEQGFETHAYDLIIASNVLHATPDLEKTMAHARSLLKPGGQMVILEITHKEHTRLGFIFGLFADWWAGVDDGRCTEPFVSFDRWDAILKRVGFSGVDSRTTDRDANLFPTSVFSTHAIDATVEYLDAPLASSGTVKDSYPPLVVVGGQTPKSQRLLNDIKAIMPPRPLQTYKRLVDLLDAEELPMKSTFVMLTELDEELFAGLTEETFEATKLLLTYSSNTVWLTENAWVQHPHQASTIGMLRSIRREHPDLGVHVLDVDAVETFDATFLVEQVLRLEEHTDELASSTTWTQEPEVSWCKGRPWIPRLKRDLARNNRMNSSRRPIYEMIDSSRAPVALQTAPDSSSYFLESAETWFVPESVRQMETKTVYVHFSCPHALRVGQLGFFYLVQGHVQEGNREVPVVALAERNASIVHVRPDYIYTEADNNLSEGGGSLIVTVLAAAVLAETVISTAKSLGVTDSILVLNPPSICGQMLLHAGEEIGLQVHLATTSGNRSSVSAGDAKSWLTLHARDTDWHLRRVLPRGVQAFVDLSADQSCECLTQRMMKVLMPGCAHYRAADLFTDTVSTELHRGLRHQASLPAAYWEHVVSLARQGLSSVSEGWEVMPCTQFAAHADKTRPDLSTVISWPRESDKATLPTRVRSIDAETLFAADKTYLLVGLTGDLGRSLGRWMVQHGACHIVLTSRNPQVNPKWLAHVEELGGRVTVLSMDVTSENSVDAGLAKIKDLHLPPVGGIAFGPLVLQDVMLKnMELPMMEMVLNPKVEGVRILHEKFSDPTSSNPLDFFVMFSSIVAVMGNPGQANYSAANCYLQALAQQRVASGLAASTIDIGAVYGVGFVTRAELEEDFNAIRFMFDSVEEHELHTLFAEAVVAGRRAVHQQEQQRKFATVLDMADLELTTGIPPLDPALKDRITFFDDPRIGNLKIPEYRGAKAGEGAAGSKGSVKEQLLQATNLDQVRQIVIDGLSAKLQVTLQIPDGESVHPTISLIDQGVDSLGAVTVGTWFSKQLYLDLPLLKVLGGASIADLADEAAARLPPSSIPLVAATDGGAESTDNTSENEVSGREDTDLSAAATITEPSSADEDDTEPGDEDVPRSHHPLSLGQEYSWRIQQGAEDPTVFNNTIGMFMKGPIDLKRLYKALRAVLRRHEIFRTGFANVDENGMAQLVFGQTKNKVQTIQVSDRAGAEEGYRQLVQTRYNPAAGDTLRLVDFFWGQDDHLLVVAYHRLVGDGSTTENIFVEAGQLYDGRSLSPRVPQFADLAARQRAMLEDGRMEEDLAYWKEMHQRPSSIPVLPLMRPLVGNSSTSNTPNFQHCGSWQQHEAVARLDPMVAFRIKERSRKHKATPMQFYLAAYQVLLARLTDSTDLTVGLADTNRATVDEMAAMGFFANLLPLRFRDFRPHITFGEHLIATRDLVREALQHARVPYGVLLDQLGLEVPVPTSNQPAPLLQAVFDYKQGQAESGTIGGAKITEVIATRERTPYDVVLEMSDDPTKDPLLTAKLQSSRYEAHHPQAFLESYMSLLSMFSMNPALKLA | Soil mold (strain NIH 2624 / FGSC A1156) | Induce G1 arrest and increased apoptotic cell populations at the sub-G1 phase | MTT assay | SW1736 | Human anaplastic thyroid cancer | MIC : 0 – 20 µM |
| dbacp04286 | Lovastatin nonaketide synthase, polyketide synthase component | MAQSMYPNEPIVVVGSGCRFPGDANTPSKLWELLQHPRDVQSRIPKERFDVDTFYHPDGKHHGRTNAPYAYVLQDDLGAFDAAFFNIQAGEAESMDPQHRLLLETVYEAVTNAGMRIQDLQGTSTAVYVGVMTHDYETVSTRDLENIPTYSATGVAVSVASNRISYFFDWHGPSMTIDTACSSSLVAVHLAVQQLRTGQSSMAIAAGANLILGPMTFVLESKLSMLSPSGRSRMWDAGADGYARGEAVCSVVLKTLSQALRDGDTIECVIRETGVNQDGRTTGITMPNHSAQEALIKATYAQAGLDITKAEDRCQFFEAHGTGTPAGDPQEAEAIATAFFGHEQVARSDGNERAPLFVGSAKTVVGHTEGTAGLAGLMKASFAVRHGVIPPNLLFDKISPRVAPFYKNLRIPTEATQWPALPPGQPRRASVNSFGFGGTNAHAIIEEYMEPEQNQLRVSNNEDCPPMTGVLSLPLVLSAKSQRSLKIMMEEMLQFLETHPEIHLHDLTWSLLRKRSVLPFRRAIVGHSHETIRRALEDAIEDGIVSSDFTTEVRGQPSVLGIFTGQGAQWPGMLKNLIEASPYVRSIVRELDDSLQSLPEKYRPSWTLLDQFMLEGEASNVQYASFSQPLCCAVQIVLVRLLEAARIRFTAVVGHSSGEIACAFAAGLISASVAIRIAYLRGVVSAGGARGTPGAMLAAGMSFEEAQEICELDAFEGRICVAASNSPDSVTFSGDANAIDHLKSMLEDESTFARLLRVDTAYHSHHMLPCADPYMQALEECGCAVADAGSPAGSVPWYSSVNAENRQMAARDVTAEYWKDNLVSPVLFSHAVQRAVVTHKALDIGIEVGCHPALKSPCVATIKDVLSGVDLAYTGCLERGKNDLDTFSRALAYLWERFGASSFDADEFMRAVAPDRPCMSVSKLLPAYPWDHSRRYWVESRATRHHLRGPKPHLLLGKLSEYSTPLSFQWLNFVRPRDIEWLDGHALQGQTVFPAAGYIVMAMEAALMIAGTHAKQVQLLEILDMSIDKAVIFDDEDSLVELNLTADVSRNAGEAGSMTISFKIDSCLSKEGNLSLSAKGQLALMIGDVNSRTTSASDQHHLPPPEEEHPHMNRVNIKAFYHELGLMGYNYSKDFRRLHnMQRADLRASGTIDFIPLMDEGNGCPLLLHPASLDVAFQTVIGAYSSPGDRRLRCLYVPTHVDRITLVPSLCLATAESGCEKVAFNTINTYDKGDYLSGDIAVFDAEQTTLFQVENITFKPFSPPDASTDHAMFARWSWGPLTPDSLLDNPEYWATAQDKEAIPIIERIVYFYIRSFLNQLTLEERQKAAFHLQKQIEWLEQVLASAKEGRHLWYDPGWENDTEAQIEHLCTANSYHPHVRLVQRVGQHLLPTVRSNGNPFDLLDHDGLLTEFYTNTLSFGPALHYARELVAQIAHRYQSMDILEIGAGTGGATKYVLATPQLGFNSYTYTDISTGFFEQAREQFAPFEDRMVFEPLDIRRSPAEQGFETHAYDLIIASNVLHATPDLEKTMAHARSLLKPGGQMVILEITHKEHTRLGFIFGLFADWWAGVDDGRCTEPFVSFDRWDAILKRVGFSGVDSRTTDRDANLFPTSVFSTHAIDATVEYLDAPLASSGTVKDSYPPLVVVGGQTPKSQRLLNDIKAIMPPRPLQTYKRLVDLLDAEELPMKSTFVMLTELDEELFAGLTEETFEATKLLLTYSSNTVWLTENAWVQHPHQASTIGMLRSIRREHPDLGVHVLDVDAVETFDATFLVEQVLRLEEHTDELASSTTWTQEPEVSWCKGRPWIPRLKRDLARNNRMNSSRRPIYEMIDSSRAPVALQTAPDSSSYFLESAETWFVPESVRQMETKTVYVHFSCPHALRVGQLGFFYLVQGHVQEGNREVPVVALAERNASIVHVRPDYIYTEADNNLSEGGGSLIVTVLAAAVLAETVISTAKSLGVTDSILVLNPPSICGQMLLHAGEEIGLQVHLATTSGNRSSVSAGDAKSWLTLHARDTDWHLRRVLPRGVQAFVDLSADQSCECLTQRMMKVLMPGCAHYRAADLFTDTVSTELHRGLRHQASLPAAYWEHVVSLARQGLSSVSEGWEVMPCTQFAAHADKTRPDLSTVISWPRESDKATLPTRVRSIDAETLFAADKTYLLVGLTGDLGRSLGRWMVQHGACHIVLTSRNPQVNPKWLAHVEELGGRVTVLSMDVTSENSVDAGLAKIKDLHLPPVGGIAFGPLVLQDVMLKnMELPMMEMVLNPKVEGVRILHEKFSDPTSSNPLDFFVMFSSIVAVMGNPGQANYSAANCYLQALAQQRVASGLAASTIDIGAVYGVGFVTRAELEEDFNAIRFMFDSVEEHELHTLFAEAVVAGRRAVHQQEQQRKFATVLDMADLELTTGIPPLDPALKDRITFFDDPRIGNLKIPEYRGAKAGEGAAGSKGSVKEQLLQATNLDQVRQIVIDGLSAKLQVTLQIPDGESVHPTISLIDQGVDSLGAVTVGTWFSKQLYLDLPLLKVLGGASIADLADEAAARLPPSSIPLVAATDGGAESTDNTSENEVSGREDTDLSAAATITEPSSADEDDTEPGDEDVPRSHHPLSLGQEYSWRIQQGAEDPTVFNNTIGMFMKGPIDLKRLYKALRAVLRRHEIFRTGFANVDENGMAQLVFGQTKNKVQTIQVSDRAGAEEGYRQLVQTRYNPAAGDTLRLVDFFWGQDDHLLVVAYHRLVGDGSTTENIFVEAGQLYDGRSLSPRVPQFADLAARQRAMLEDGRMEEDLAYWKEMHQRPSSIPVLPLMRPLVGNSSTSNTPNFQHCGSWQQHEAVARLDPMVAFRIKERSRKHKATPMQFYLAAYQVLLARLTDSTDLTVGLADTNRATVDEMAAMGFFANLLPLRFRDFRPHITFGEHLIATRDLVREALQHARVPYGVLLDQLGLEVPVPTSNQPAPLLQAVFDYKQGQAESGTIGGAKITEVIATRERTPYDVVLEMSDDPTKDPLLTAKLQSSRYEAHHPQAFLESYMSLLSMFSMNPALKLA | Soil mold (strain NIH 2624 / FGSC A1156) | Induce G1 arrest and increased apoptotic cell populations at the sub-G1 phase | MTT assay | 8305C | Human anaplastic thyroid cancer | MIC : 0 – 20 µM |
| dbacp06381 | TT 1 | KIKAVLKVLTT | Venom base | Inducing apoptosis | MTT assay | TT | Thyroid cancer | IC50 : 18.23 ± 2.81 μg/ml |
| dbacp06382 | TT 1 | KIKAVLKVLTT | Venom base | Inducing apoptosis | MTT assay | TT | Thyroid cancer | IC50 : 3.87 ± 0.34 μg/ml |
| dbacp06383 | TT 1 | KIKAVLKVLTT | Venom base | Inducing apoptosis | MTT assay | TT | Thyroid cancer | IC50 : 2.76 ± 0.32 μg/ml |