2 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp05596 | Polyphemusin II | RRWCFRVCYKGFCYRKCR-NH2 | Atlantic horseshoe crab | Induce necrotic cell death | Cell viability assay | K562 | Human erythroleukemia | EC50 : 22 μM |
| dbacp05597 | Polyphemusin III | RRGCFRVCYRGFCFQRCR | Atlantic horseshoe crab | Induce permeabilization of the cytoplasmic membrane | Trypan blue exclusion assay and Lactate dehydrogenase(LDH)-release assay | HL-60 | Human cervical cancer | IC50 : < 10 μM |