14 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp04643 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :3.2 ± 0.1 µM |
| dbacp04644 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :2.1 ± 0.1 µM |
| dbacp04645 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :1.8 ± 0.1 µM |
| dbacp04646 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic peptide | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 :1.4 ± 0.1 µM |
| dbacp04647 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 1.4 ± 0.1 µM |
| dbacp04648 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 3.2 ± 0.1 µM |
| dbacp04649 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 2.1 ± 0.1 µM |
| dbacp04650 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 1.8 ± 0.1 µM |
| dbacp04651 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Natural component of bee venom | Physical membrane disruption | MTT/MTS assay | E42/02 | Skin cancer | IC50 : 1.4 ± 0.1 µM |
| dbacp04652 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Main component of honey bee venom | Membrane damage; Apoptotic cell death; Necrosis | Cell viability assay | SCC25 | Skin cancer | 102.9 ± 4.1% cell growth inhibition at 1 µM |
| dbacp04653 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Venom base | Inducing apoptosis | MTT assay | SGC-7901 | Gastric cancer | Not found |
| dbacp04654 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Honey bee | Membrane damage as swelling; Breakage or blebbing | Live/Dead staining and florescence microscopy assay | AGS | Human adenocarcinoma | MIC : 10 μg/mL |
| dbacp04655 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Honey bee | Membrane damage as swelling; Breakage or blebbing | Live/Dead staining and florescence microscopy assay | COLO205 | Human adenocarcinoma | MIC : 10 μg/mL |
| dbacp04656 | Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ | Honey bee | Membrane damage as swelling; Breakage or blebbing | Live/Dead staining and florescence microscopy assay | HCT-15 | Human adenocarcinoma | MIC : 5 μg/mL |