dbACP: A Comprehensive Database of Anti-Cancer Peptides

33 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp01333 Aurein-2.5 GLFDIVKKVVGAFGSL Green and golden bell frog Cell membrane disintegration One-dose and five-dose assay M14 Melanoma IC50 : 5 μM
dbacp01385 Aurein-3.3 [Cleaved into: Aurein-3.3.1] GLFDIVKKIAGHIVSSI Southern bell frog Cell membrane disintegration One-dose and five-dose assay KM12 Colon cancer IC50 : 4 - 5 μM
dbacp02020 Buforin IIb RAGLQFPVGRLLRRLLRRLLR Histone H2A Inducing mitochondria-dependent apoptosis MTT/MTS assay M14 Skin cancer IC50 : 15.1 µg/ml
dbacp02043 Buforin IIb RAGLQFPVGRLLRRLLRRLLR Histone H2A Inducing mitochondria-dependent apoptosis MTT/MTS assay KM12 Colon cancer IC50 : 12 µg/ml
dbacp02078 Buforin Iib RAGLQFPVGRLLRRLLRRLLR Not found Inducing apoptosis MTT/MTS assay M14 Not specified IC50 : 15.1 µg/ml
dbacp02101 Buforin Iib RAGLQFPVGRLLRRLLRRLLR Not found Inducing apoptosis MTT/MTS assay KM12 Not specified IC50 : 12 µg/ml
dbacp02273 Camel KWKLFKKIGAVLKVL Ceropin-Melittin hybrid Cell swelling and rupture of the plasma membrane MTT/MTS assay WM1158 Skin cancer LC50 : 4.1 µM
dbacp02644 Defensin-like protein (Sesquin) KTCENLADTY Yard-Long bean Anti-proliferative action MTT assay M1 Breast cancer MIC : 0.125 μg/ml
dbacp03711 Laxaphycin A Aoc-Hse-E-Dhb-Hyp-Hse-FLIILG Terrestrial blue-green alga or the marine cyanobacterium Not specified Cell viability assay CEM-VM1 Leukemia cancer No inhibition at 4 µM
dbacp03714 Laxaphycin B A-Hleu-QN-MeIle-Hasn-TPLT-Ade-V-Hleu Terrestrial blue-green alga or the marine cyanobacterium Not specified Cell viability assay CEM-VM1 Leukemia cancer 44% inhibition at 1 µM
dbacp03717 Laxaphycin B A-Hleu-QN-MeIle-Hasn-TPLT-Ade-V-Hleu Terrestrial blue-green alga or the marine cyanobacterium Not specified Cell viability assay CEM-VM1 Leukemia cancer 40% inhibition at 1 µM
dbacp05038 P18 KWKLFKKIPKFLHLAKKF Bovine lactoferrin (Lf-B) Necrosis; Cell membrane rupture MTT/MTS assay M14 Skin cancer 92.2 ± 1.02% cell viability at 10 µM
dbacp05039 P18 KWKLFKKIPKFLHLAKKF Synthetic peptide Necrosis; Cell membrane rupture MTT/MTS assay M14 Skin cancer 71.1 ± 2.84% cell viability at 20 µM
dbacp05040 P18 KWKLFKKIPKFLHLAKKF Synthetic peptide Necrosis; Cell membrane rupture MTT/MTS assay M14 Skin cancer 50 ± 3.09% cell viability at 40 µM
dbacp05041 P18 KWKLFKKIPKFLHLAKKF Synthetic peptide Necrosis; Cell membrane rupture MTT/MTS assay M14 Skin cancer 31.5 ± 1.49% cell viability at 60 µM
dbacp05042 P18 KWKLFKKIPKFLHLAKKF Synthetic peptide Necrosis; Cell membrane rupture MTT/MTS assay M14 Skin cancer 13.8 ± 1.44% cell viability at 80 µM
dbacp07580 R-DIM-P-LF11 FQWQRNIRKVRPRVKRINRQWQF Synthetic Peptides target phosphatidylserine, trigger apoptosis MTS assay WM164 Skin Cancer LC50 = 20.9 ± 3.9 μM
dbacp07583 R-DIM-P-LF11-322 PFWRIRIRRPRRIRIRWFP Synthetic Peptides target phosphatidylserine, trigger apoptosis MTS assay WM164 Skin Cancer LC50 = 4.7 ± 0.2 μM
dbacp07586 DIM-LF11-322 PFWRIRIRRPFWRIRIRR Synthetic Peptides target phosphatidylserine, trigger apoptosis MTS assay WM164 Skin Cancer LC50 = 4.6 ± 0.1 μM
dbacp07589 R-DIM-P-LF11-215 FWRIRIRRPRRIRIRWF Synthetic Peptides target phosphatidylserine, trigger apoptosis MTS assay WM164 Skin Cancer LC50 = 4.6 ± 0.1 μM
dbacp07592 R-DIM-P-LF11-334 PWRIRIRRPRRIRIWP Synthetic Peptides target phosphatidylserine, trigger apoptosis MTS assay WM164 Skin Cancer LC50 = 5.0 ± 0.1 μM
dbacp07595 R-DIM-LF11-334-LF11-334 PWRIRIRRRRIRIRWPPWRIRIRR Synthetic Peptides target phosphatidylserine, trigger apoptosis MTS assay WM164 Skin Cancer LC50 = 3.6 ± 0.7 μM
dbacp07598 DIM-LF11-339 RRWFWRRRRWFWRR Synthetic Peptides target phosphatidylserine, trigger apoptosis MTS assay WM164 Skin Cancer LC50 = 3.8 ± 0.3 μM
dbacp07805 cT1 KWCFRVCYRGICYRRCRG Synthetic Not Available Resazurin dye assay WM164 Skin Cancer CC50 = 2.7 ± 0.1 µM
dbacp07810 [R/K]cT1 KWCFKVCYKGICYKKCKG Synthetic Not Available Resazurin dye assay WM164 Skin Cancer CC50 = 4.3 ± 0.3 µM
dbacp07816 [W2S]cT1 KSCFRVCYRGICYRRCRG Synthetic Not Available Resazurin dye assay WM164 Skin Cancer CC50 = 3.9 ± 0.2 µM
dbacp07822 [Y8S-I11S]cT1 KWCFRVCSRGSCYRRCRG Synthetic Not Available Resazurin dye assay WM164 Skin Cancer CC50 = 28.2 ± 2.0 µM
dbacp07827 [R14S]cT1 KWCFRVCYRGICYSRCRG Synthetic Not Available Resazurin dye assay WM164 Skin Cancer CC50 = 2.7 ± 0.1 µM
dbacp07832 [R17S]cT1 KWCFRVCYRGICYRRCSG Synthetic Not Available Resazurin dye assay WM164 Skin Cancer CC50 = 1.8 ± 0.1 µM
dbacp07836 [R9S-R14S-R17S]cT1 KWCFRVCYSGICYSRCSG Synthetic Not Available Resazurin dye assay WM164 Skin Cancer CC50 = 11.1 ± 0.9 µM
dbacp07840 [G18K]cT1 KWCFRVCYRGICYRRCRK Synthetic Not Available Resazurin dye assay WM164 Skin Cancer CC50 = 2.7 ± 0.2 µM
dbacp07845 [I11F-G18K]cT1 KWCFRVCYRGFCYRRCRK Synthetic Not Available Resazurin dye assay WM164 Skin Cancer CC50 = 2.9 ± 0.2 µM
dbacp07947 IL13Rα2 D1 peptide GSETWKTIITKN Synthetic IL13Rα2 blockade inhibits cancer metastasis MTT assay KM12SM Colorectal Cancer inhibited IL13-stimulated cell adhesion