dbACP: A Comprehensive Database of Anti-Cancer Peptides

11 result(s) have been found!

Accession Name Sequence Source/Organism Mechanism Assay Type Cell Line Cancer Type Activity
dbacp06903 CIGB-300 GRKKRRQRRRPPQ-X-CWMSPRHLGTC Synthetic Cell Penetration Crystal Violet assay NCI-H-460 Lung Cancer IC50 = 30 ± 5.3 µM
dbacp06942 HTDT-6-2-3-2 GPLGAGP Enteromorpha prolifera Apoptosis inducing CCK-8 assay NCI-H-460 Lung Cancer IC50 = 0.3686 ± 0.0935 mg/mL
dbacp07244 CIGB-552 HARIKpTFRRlKWKYKGKFW Synthetic NF-κB inhibition enhances cisplatin synergy Sulforhodamine B assay NCI-H-460 Lung Cancer IC50 = 287.9 μM
dbacp07877 Fi-Histin1-21 SRSSRAGLQFPVGRIHRLLRK Fenneropenaeus indicus Membrane disruption and DNA binding XTT assay NCI-H-460 Lung Cancer IC50 = 22.670 ± 13.939 μM
dbacp07995 [G10a]SHa FLSGIVGMLaKLF Synthetic analogue of Temporin-1SHa Enhanced cationicity/hydrophobicity increases cytotoxicity MTT assay NCI-H-460 Lung Cancer IC50 =24.3 ± 0.8 µM
dbacp07998 [G10a]SHa-BCTP FLSGIVGMLaKLFLFKQYAELW Synthetic analogue of Temporin-1SHa Enhanced cationicity/hydrophobicity increases cytotoxicity MTT assay NCI-H-460 Lung Cancer IC50 >100 µM
dbacp08001 [G4a]SHa FLSaIVGMLGKLF Synthetic analogue of Temporin-1SHa Enhanced cationicity/hydrophobicity increases cytotoxicity MTT assay NCI-H-460 Lung Cancer IC50 >100 µM
dbacp08004 [G7a]SHa FLSGIVaMLGKLF Synthetic analogue of Temporin-1SHa Enhanced cationicity/hydrophobicity increases cytotoxicity MTT assay NCI-H-460 Lung Cancer IC50 >100 µM
dbacp08007 [G4,7a]SHa FLSaIVaMLGKLF Synthetic analogue of Temporin-1SHa Enhanced cationicity/hydrophobicity increases cytotoxicity MTT assay NCI-H-460 Lung Cancer IC50 = 37.3 ± 3.5 µM
dbacp08010 [G4,7,10a]SHa FLSaIVaMLaKLF Synthetic analogue of Temporin-1SHa Enhanced cationicity/hydrophobicity increases cytotoxicity MTT assay NCI-H-460 Lung Cancer IC50 >100 µM
dbacp08013 [G7,10a]SHa FLSGIVaMLaKLF Synthetic analogue of Temporin-1SHa Enhanced cationicity/hydrophobicity increases cytotoxicity MTT assay NCI-H-460 Lung Cancer IC50 >100 µM