233 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp06639 | C-Mel | CGIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic analogue | Plasma memberane pore formation | MTT assay | HeLa | Cervical Cancer | IC50 = 64.15 µg/mL |
| dbacp06640 | C-Mel | CGIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic analogue | Plasma memberane pore formation | MTT assay | C-33A | Cervical Cancer | IC50 = 44.76 µg/mL |
| dbacp06641 | C-Mel | CGIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic analogue | Plasma memberane pore formation | MTT assay | MCF-7 | Breast Cancer | IC50 = 110.59 µg/mL |
| dbacp06642 | CM–FA | CGIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic analogue | Plasma memberane pore formation | MTT assay | HeLa | Cervical Cancer | IC50 = 67.34 µg/mL |
| dbacp06643 | CM–FA | CGIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic analogue | Plasma memberane pore formation | MTT assay | C-33A | Cervical Cancer | IC50 = 35.75 µg/mL |
| dbacp06644 | CM–FA | CGIGAVLKVLTTGLPALISWIKRKRQQ | Synthetic analogue | Plasma memberane pore formation | MTT assay | MCF-7 | Breast Cancer | IC50 = 10.38 µg/mL |
| dbacp06645 | Mel-C | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | HeLa | Cervical Cancer | IC50 = 50.72 µg/mL |
| dbacp06646 | Mel-C | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | C-33A | Cervical Cancer | IC50 = 58.63 µg/mL |
| dbacp06647 | Mel-C | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | MCF-7 | Breast Cancer | IC50 = 160.62 µg/mL |
| dbacp06648 | MC–FA | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | HeLa | Cervical Cancer | IC50 = 66.43 µg/mL |
| dbacp06649 | MC–FA | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | C-33A | Cervical Cancer | IC50 = 35.22 µg/ mL |
| dbacp06650 | MC–FA | GIGAVLKVLTTGLPALISWIKRKRQQC | Synthetic analogue | Plasma memberane pore formation | MTT assay | MCF-7 | Breast Cancer | IC50 = 12.63 µg/mL |
| dbacp06777 | BK-1 | rRP-Hyp-G-Thi-S-Apc-Thi-R | Synthetic analogue of Bradykinin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06778 | BK-2 | rRP-Hyp-G-Thi-S-f-Apc-R | Synthetic analogue of Bradykinin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06779 | BK-3 | Aaa-rRP-Hyp-G-Thi-S-Acc-Thi-R | Synthetic analogue of Bradykinin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06780 | BK-4 | Aaa-rRP-Hyp-G-Thi-S-f-Acc-R | Synthetic analogue of Bradykinin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06781 | BK-5 | rRP-Hyp-G-Thi-S-f-(L)Pip-R | Synthetic analogue of Bradykinin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06782 | BK-6 | Aaa-rRP-Hyp-G-Thi-S-(D)Pip-(L)Pip-R | Synthetic analogue of Bradykinin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06783 | BK-7 | rRP-Hyp-G-Thi-S-(D)Pip-Thi-R | Synthetic analogue of Bradykinin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06784 | BK-8 | Aaa-rRP-Hyp-G-Thi-S-(D)Pip-Thi-R | Synthetic analogue of Bradykinin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06785 | NT-9 | RRPYIL | Synthetic analogue of Neurotensin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06786 | NT-10 | RRPAIL | Synthetic analogue of Neurotensin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06787 | NT-11 | RRPYAL | Synthetic analogue of Neurotensin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06788 | NT-12 | PEGRKPY-Tle-L | Synthetic analogue of Neurotensin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06789 | NT-12 | PEGKRPY-Tle-L | Synthetic analogue of Neurotensin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06790 | NT-12 | PEGKKPY-Tle-L | Synthetic analogue of Neurotensin | Not available | MTS assay | HCT-116 | Colorectal Cancer | Not Available |
| dbacp06803 | [C/U, G1K, L5Y, K8R]cGm | KURRYUYRQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | CRL-1739 | Gastric Cancer | CC50 = 46.2 ± 7.6 μM |
| dbacp06804 | [C/U, G1K, L5Y, K8R]cGm | KURRYUYRQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 2.3 ± 0.2 μM |
| dbacp06805 | [C/U, G1K, L5Y, K8R]cGm | KURRYUYRQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HeLa | Cervical Cancer | CC50 = 36.2 ± 2.8 μM |
| dbacp06806 | [C/U, G1K, L5Y, K8R]cGm | KURRYUYRQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MCF-7 | Breast Cancer | CC50 = 29.0 ± 3.7 μM |
| dbacp06807 | [C/U, G1K, L5Y, K8R]cGm | KURRYUYRQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | K-562 | Leukemia Cancer | CC50 = 6.4 ± 0.6 μM |
| dbacp06808 | [C/U, G1K, L5Y, K8R]cGm | KURRYUYRQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HL-60 | Leukemia Cancer | CC50 = 33.3 ±7.4μM |
| dbacp06809 | [G1K, L5Y, K8R]cGm | KCRRYCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | CRL-1739 | Gastric Cancer | CC50 = 26.5 ± 2.4 μM |
| dbacp06810 | [G1K, L5Y, K8R]cGm | KCRRYCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 2.0 ± 0.1 μM |
| dbacp06811 | [G1K, L5Y, K8R]cGm | KCRRYCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HeLa | Cervical Cancer | CC50 = 20.9 ± 1.4 μM |
| dbacp06812 | [G1K, L5Y, K8R]cGm | KCRRYCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MCF-7 | Breast Cancer | CC50 = 15.2 ± 1.9 μM |
| dbacp06813 | [G1K, L5Y, K8R]cGm | KCRRYCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | K-562 | Leukemia Cancer | CC50 = 1.3 ± 0.1 μM |
| dbacp06814 | [G1K, L5Y, K8R]cGm | KCRRYCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HL-60 | Leukemia Cancer | CC50 = 15.7 ±1.1μM |
| dbacp06815 | [D-P L-P]cGm | GCRRLCYKQRCVTYCRGpPR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | CRL-1739 | Gastric Cancer | CC50 = 22.5 ± 3.3 μM |
| dbacp06816 | [D-P L-P]cGm | GCRRLCYKQRCVTYCRGpPR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 3.0 ± 0.1 μM |
| dbacp06817 | [D-P L-P]cGm | GCRRLCYKQRCVTYCRGpPR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HeLa | Cervical Cancer | CC50 = 51.5 ± 3.9 μM |
| dbacp06818 | [D-P L-P]cGm | GCRRLCYKQRCVTYCRGpPR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | K-562 | Leukemia Cancer | CC50 = 3.9 ± 0.2 μM |
| dbacp06819 | [C/U]cGm | GURRLUYKQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | CRL-1739 | Gastric Cancer | CC50 = 51.0 ± 4.6 μM |
| dbacp06820 | [C/U]cGm | GURRLUYKQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 4.6 ± 0.2 μM |
| dbacp06821 | [C/U]cGm | GURRLUYKQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HeLa | Cervical Cancer | CC50 > 64 μM |
| dbacp06822 | [C/U]cGm | GURRLUYKQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MCF-7 | Breast Cancer | CC50 = 37.5 ± 3.3 μM |
| dbacp06823 | [C/U]cGm | GURRLUYKQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | K-562 | Leukemia Cancer | CC50 = 1.4 ± 0.2 μM |
| dbacp06824 | [C/U]cGm | GURRLUYKQRUVTYURGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HL-60 | Leukemia Cancer | CC50 = 38.5 ± 4.8 μM |
| dbacp06825 | [G1K, K8R]cGm | KCRRLCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | CRL-1739 | Gastric Cancer | CC50 = 19.5 ± 0.5 μM |
| dbacp06826 | [G1K, K8R]cGm | KCRRLCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 1.7 ± 0.1 μM |
| dbacp06827 | [G1K, K8R]cGm | KCRRLCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HeLa | Cervical Cancer | CC50 = 44.2 ± 2.2μM |
| dbacp06828 | [G1K, K8R]cGm | KCRRLCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MCF-7 | Breast Cancer | CC50 = 6.7 ± 0.7 μM |
| dbacp06829 | [G1K, K8R]cGm | KCRRLCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | K-562 | Leukemia Cancer | CC50 = 2.1 ± 0.2 μM |
| dbacp06830 | [G1K, K8R]cGm | KCRRLCYRQRCVTYCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HL-60 | Leukemia Cancer | CC50 = 9.0 ± 1.1μM |
| dbacp06831 | [R4A, R18A]cGm | GCRALCYKQRCVTYCRGA | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | CRL-1739 | Gastric Cancer | CC50 > 64 μM |
| dbacp06832 | [R4A, R18A]cGm | GCRALCYKQRCVTYCRGA | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 10.3 ± 1.1 μM |
| dbacp06833 | [R4A, R18A]cGm | GCRALCYKQRCVTYCRGA | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HeLa | Cervical Cancer | CC50 > 64 μM |
| dbacp06834 | [R4A, R18A]cGm | GCRALCYKQRCVTYCRGA | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MCF-7 | Breast Cancer | CC50 = 48.4 ± 0.7 μM |
| dbacp06835 | [R4A, R18A]cGm | GCRALCYKQRCVTYCRGA | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | K-562 | Leukemia Cancer | CC50 = 11.5 ± 0.6 μM |
| dbacp06836 | [R4A, R18A]cGm | GCRALCYKQRCVTYCRGA | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HL-60 | Leukemia Cancer | CC50 = 34.1 ± 3.9 μM |
| dbacp06837 | [Y7W, K8R, Y14W]cGm | GCRRLCWRQRCVTWCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | CRL-1739 | Gastric Cancer | CC50 = 31.6 ± 1.3 μM |
| dbacp06838 | [Y7W, K8R, Y14W]cGm | GCRRLCWRQRCVTWCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MM96L | Skin Cancer | CC50 = 5.4 ± 0.3 μM |
| dbacp06839 | [Y7W, K8R, Y14W]cGm | GCRRLCWRQRCVTWCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | HeLa | Cervical Cancer | CC50 = 41.0 ± 4.2 μM |
| dbacp06840 | [Y7W, K8R, Y14W]cGm | GCRRLCWRQRCVTWCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | MCF-7 | Breast Cancer | CC50 = 15.1 ± 1.4 μM |
| dbacp06841 | [Y7W, K8R, Y14W]cGm | GCRRLCWRQRCVTWCRGR | Synthetic Analogue of Gomesin | Cell membrane penetration | Resazurin dye assay | K-562 | Leukemia Cancer | CC50 = 3.9 ± 0.1 μM |
| dbacp06871 | RR-1-RR | RRWQWRWQWRR | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MCF-7 | Breast Cancer | IC50 = 58 µM |
| dbacp06872 | RR-1-RR | RRWQWRWQWRR | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MDA-MB-231 | Breast Cancer | IC50 = 67 µM |
| dbacp06873 | R-1-RR | RWQWRWQWRR | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MCF-7 | Breast Cancer | IC50 = 122 µM |
| dbacp06874 | R-1-RR | RWQWRWQWRR | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MDA-MB-231 | Breast Cancer | IC50 = 95 µM |
| dbacp06875 | RR-1-R | RRWQWRWQWR | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MCF-7 | Breast Cancer | IC50 = 68 µM |
| dbacp06876 | RR-1-R | RRWQWRWQWR | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MDA-MB-231 | Breast Cancer | IC50 = 73 µM |
| dbacp06877 | 1 | WQWRWQW | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MCF-7 | Breast Cancer | IC50 = 105 µM |
| dbacp06878 | 1 | WQWRWQW | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MDA-MB-231 | Breast Cancer | IC50 > 170 µM |
| dbacp06879 | R-1 | RWQWRWQW | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MCF-7 | Breast Cancer | IC50 = 58 µM |
| dbacp06880 | R-1 | RWQWRWQW | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MDA-MB-231 | Breast Cancer | IC50 > 150 µM |
| dbacp06881 | 1-R | WQWRWQWR | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MCF-7 | Breast Cancer | IC50 = 130 µM |
| dbacp06882 | 1-R | WQWRWQWR | Synthetic analogue of LfcinB(21-25)Pal | Apoptosis inducing | MTT assay | MDA-MB-231 | Breast Cancer | IC50 > 150 µM |
| dbacp06913 | AC-P19M | FAKKLAKLKKKLAKLAKKR | Synthetic analogue of AC-P19 | Inhibition of cell signalling | WST-8 assay | A-549 | Lung Cancer | IC50 = 9.84 µM |
| dbacp06914 | AC-P19M | FAKKLAKLKKKLAKLAKKR | Synthetic analogue of AC-P19 | Inhibition of cell signalling | WST-8 assay | H-460 | Lung Cancer | IC50 = 6.29 µM |
| dbacp07668 | Longicalycinin A linear analogue 1 | GYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.66 ± 0.0007 µg/ml |
| dbacp07669 | Longicalycinin A linear analogue 1 | GYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.45 ± 0.0042 µg/ml |
| dbacp07670 | Longicalycinin A linear analogue 1 | GYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 13.29% Cell death at 100 µg/ml |
| dbacp07671 | Longicalycinin A linear analogue 1 | GYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 83.02% Cell death at 100 µg/ml |
| dbacp07672 | Longicalycinin A Cyclic analogue 1 | GYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.2 ± 0.007 µg/ml |
| dbacp07673 | Longicalycinin A Cyclic analogue 1 | GYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 11.4 ± 0.0028 µg/ml |
| dbacp07674 | Longicalycinin A Cyclic analogue 1 | GYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 69.73% Cell death at 100 µg/ml |
| dbacp07675 | Longicalycinin A Cyclic analogue 1 | GYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 71.5% Cell death at 100 µg/ml |
| dbacp07676 | Longicalycinin A linear analogue 2 | LYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 8.76 ± 0.0035 µg/ml |
| dbacp07677 | Longicalycinin A linear analogue 2 | LYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 12.33 ± 0 µg/ml |
| dbacp07678 | Longicalycinin A linear analogue 2 | LYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 71.37% Cell death at 100 µg/ml |
| dbacp07679 | Longicalycinin A linear analogue 2 | LYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 88.47% Cell death at 100 µg/ml |
| dbacp07687 | Longicalycinin A linear analogue 14 | PYFFL | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.67 ± 0.0007 µg/ml |
| dbacp07688 | Longicalycinin A linear analogue 14 | PYFFL | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 9.12 ± 0.0042 µg/ml |
| dbacp07689 | Longicalycinin A linear analogue 14 | PYFFL | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 13.02% Cell death at 100 µg/ml |
| dbacp07690 | Longicalycinin A linear analogue 14 | PYFFL | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 82.36% Cell death at 100 µg/ml |
| dbacp07691 | Longicalycinin A cyclic analogue 14 | PYFFL | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.46 ± 0.0028 µg/ml |
| dbacp07692 | Longicalycinin A cyclic analogue 14 | PYFFL | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.92 ± 0.0021 µg/ml |
| dbacp07693 | Longicalycinin A cyclic analogue 14 | PYFFL | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 70.69% Cell death at 100 µg/ml |
| dbacp07694 | Longicalycinin A cyclic analogue 14 | PYFFL | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 52.38% Cell death at 100 µg/ml |
| dbacp07695 | Longicalycinin A linear analogue 3 | GYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.77 ± 0.0007 µg/ml |
| dbacp07696 | Longicalycinin A linear analogue 3 | GYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 11.4 ± 0 µg/ml |
| dbacp07697 | Longicalycinin A linear analogue 3 | GYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 82.33% Cell death at 100 µg/ml |
| dbacp07698 | Longicalycinin A linear analogue 3 | GYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 87.56% Cell death at 100 µg/ml |
| dbacp07699 | Longicalycinin A cyclic analogue 3 | GYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.5 ± 0.0056 µg/ml |
| dbacp07700 | Longicalycinin A cyclic analogue 3 | GYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 11.28 ± 0.0063 µg/ml |
| dbacp07701 | Longicalycinin A cyclic analogue 3 | GYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 56.72% Cell death at 100 µg/ml |
| dbacp07702 | Longicalycinin A cyclic analogue 3 | GYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 28.51% Cell death at 100 µg/ml |
| dbacp07703 | Longicalycinin A linear analogue 4 | AYPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.53 ± 0.0014 µg/ml |
| dbacp07704 | Longicalycinin A linear analogue 4 | AYPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.78 ± 0.0021 µg/ml |
| dbacp07705 | Longicalycinin A linear analogue 4 | AYPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 27.13% Cell death at 100 µg/ml |
| dbacp07706 | Longicalycinin A linear analogue 4 | AYPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 75.91% Cell death at 100 µg/ml |
| dbacp07707 | Longicalycinin A cyclic analogue 4 | AYPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.77 ± 0.007 µg/ml |
| dbacp07708 | Longicalycinin A cyclic analogue 4 | AYPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 11.33 ± 0.0035 µg/ml |
| dbacp07709 | Longicalycinin A cyclic analogue 4 | AYPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 71.1% Cell death at 100 µg/ml |
| dbacp07710 | Longicalycinin A cyclic analogue 4 | AYPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 52.49% Cell death at 100 µg/ml |
| dbacp07711 | Longicalycinin A linear analogue 5 | FSPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 8.99 ± 0.0014 µg/ml |
| dbacp07712 | Longicalycinin A linear analogue 5 | FSPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.97 ± 0.0049 µg/ml |
| dbacp07713 | Longicalycinin A linear analogue 5 | FSPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 76.72% Cell death at 100 µg/ml |
| dbacp07714 | Longicalycinin A linear analogue 5 | FSPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 91.52% Cell death at 100 µg/ml |
| dbacp07715 | Longicalycinin A cyclic analogue 5 | FSPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.45 ± 0.0056 µg/ml |
| dbacp07716 | Longicalycinin A cyclic analogue 5 | FSPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 9.98 ± 0.4256 µg/ml |
| dbacp07717 | Longicalycinin A cyclic analogue 5 | FSPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 41.37% Cell death at 100 µg/ml |
| dbacp07718 | Longicalycinin A cyclic analogue 5 | FSPFG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 97.74% Cell death at 100 µg/ml |
| dbacp07719 | Longicalycinin A linear analogue 6 | VYPIA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.98 ± 0.0014 µg/ml |
| dbacp07720 | Longicalycinin A linear analogue 6 | VYPIA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 12.31 ± 0.0063 µg/ml |
| dbacp07721 | Longicalycinin A linear analogue 6 | VYPIA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 38.64% Cell death at 100 µg/ml |
| dbacp07722 | Longicalycinin A linear analogue 6 | VYPIA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 49.33% Cell death at 100 µg/ml |
| dbacp07723 | Longicalycinin A cyclic analogue 6 | VYPIA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 17.34 ± 0.0014 µg/ml |
| dbacp07724 | Longicalycinin A cyclic analogue 6 | VYPIA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.2 ± 0.0021 µg/ml |
| dbacp07725 | Longicalycinin A cyclic analogue 6 | VYPIA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 51.79% Cell death at 100 µg/ml |
| dbacp07726 | Longicalycinin A cyclic analogue 6 | VYPIA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 27.61% Cell death at 100 µg/ml |
| dbacp07727 | Longicalycinin A linear analogue 7 | PYVFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.6 ± 0.0007 µg/ml |
| dbacp07728 | Longicalycinin A linear analogue 7 | PYVFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 9.78 ± 0.0212 µg/ml |
| dbacp07729 | Longicalycinin A linear analogue 7 | PYVFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 82.33% Cell death at 100 µg/ml |
| dbacp07730 | Longicalycinin A linear analogue 7 | PYVFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 84.17% Cell death at 100 µg/ml |
| dbacp07731 | Longicalycinin A cyclic analogue 7 | PYVFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.21 ± 0.0056 µg/ml |
| dbacp07732 | Longicalycinin A cyclic analogue 7 | PYVFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 12.11 ± 0.0035 µg/ml |
| dbacp07733 | Longicalycinin A cyclic analogue 7 | PYVFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 47.68% Cell death at 100 µg/ml |
| dbacp07734 | Longicalycinin A cyclic analogue 7 | PYVFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 22.86% Cell death at 100 µg/ml |
| dbacp07735 | Longicalycinin A linear analogue 8 | FYPVG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.35 ± 0.0014 µg/ml |
| dbacp07736 | Longicalycinin A linear analogue 8 | FYPVG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 12.88 ± 0.0014 µg/ml |
| dbacp07737 | Longicalycinin A linear analogue 8 | FYPVG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 15.35% Cell death at 100 µg/ml |
| dbacp07738 | Longicalycinin A linear analogue 8 | FYPVG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 88.01% Cell death at 100 µg/ml |
| dbacp07739 | Longicalycinin A cyclic analogue 8 | FYPVG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.12 ± 0.0007 µg/ml |
| dbacp07740 | Longicalycinin A cyclic analogue 8 | FYPVG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 12.67 ± 0.0028 µg/ml |
| dbacp07741 | Longicalycinin A cyclic analogue 8 | FYPVG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 36.85% Cell death at 100 µg/ml |
| dbacp07742 | Longicalycinin A cyclic analogue 8 | FYPVG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 29.87% Cell death at 100 µg/ml |
| dbacp07743 | Longicalycinin A linear analogue 9 | FYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.33 ± 0.0007 µg/ml |
| dbacp07744 | Longicalycinin A linear analogue 9 | FYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.44 ± 0.5536 µg/ml |
| dbacp07745 | Longicalycinin A linear analogue 9 | FYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 72.74% Cell death at 100 µg/ml |
| dbacp07746 | Longicalycinin A linear analogue 9 | FYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 1.59% Cell death at 100 µg/ml |
| dbacp07747 | Longicalycinin A cyclic analogue 9 | FYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.67 ± 0 µg/ml |
| dbacp07748 | Longicalycinin A cyclic analogue 9 | FYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.7 ± 0.0056 µg/ml |
| dbacp07749 | Longicalycinin A cyclic analogue 9 | FYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 73.98% Cell death at 100 µg/ml |
| dbacp07750 | Longicalycinin A cyclic analogue 9 | FYPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 76.25% Cell death at 100 µg/ml |
| dbacp07751 | Longicalycinin A linear analogue 10 | FYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.5 ± 0.0014 µg/ml |
| dbacp07752 | Longicalycinin A linear analogue 10 | FYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.5 ± 0.0007 µg/ml |
| dbacp07753 | Longicalycinin A linear analogue 10 | FYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 76.72% Cell death at 100 µg/ml |
| dbacp07754 | Longicalycinin A linear analogue 10 | FYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 92.09% Cell death at 100 µg/ml |
| dbacp07755 | Longicalycinin A cyclic analogue 10 | FYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.28 ± 0 µg/ml |
| dbacp07756 | Longicalycinin A cyclic analogue 10 | FYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 11.56 ± 0.0028 µg/ml |
| dbacp07757 | Longicalycinin A cyclic analogue 10 | FYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 72.06% Cell death at 100 µg/ml |
| dbacp07758 | Longicalycinin A cyclic analogue 10 | FYPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 71.27% Cell death at 100 µg/ml |
| dbacp07759 | Longicalycinin A linear analogue 11 | TVPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.56 ± 0.0021 µg/ml |
| dbacp07760 | Longicalycinin A linear analogue 11 | TVPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 11.67 ± 0.0014 µg/ml |
| dbacp07761 | Longicalycinin A linear analogue 11 | TVPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 70.28% Cell death at 100 µg/ml |
| dbacp07762 | Longicalycinin A linear analogue 11 | TVPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 88.47% Cell death at 100 µg/ml |
| dbacp07763 | Longicalycinin A cyclic analogue 11 | TVPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.36 ± 0 µg/ml |
| dbacp07764 | Longicalycinin A cyclic analogue 11 | TVPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.61 ± 0.0007 µg/ml |
| dbacp07765 | Longicalycinin A cyclic analogue 11 | TVPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 72.06% Cell death at 100 µg/ml |
| dbacp07766 | Longicalycinin A cyclic analogue 11 | TVPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 74.89% Cell death at 100 µg/ml |
| dbacp07767 | Longicalycinin A linear analogue 12 | FYPFI | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 11.32 ± 0.0014 µg/ml |
| dbacp07768 | Longicalycinin A linear analogue 12 | FYPFI | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 14.2 ± 0.0014 µg/ml |
| dbacp07769 | Longicalycinin A linear analogue 12 | FYPFI | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 12.06% Cell death at 100 µg/ml |
| dbacp07770 | Longicalycinin A linear analogue 12 | FYPFI | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 81.34% Cell death at 100 µg/ml |
| dbacp07771 | Longicalycinin A cyclic analogue 12 | FYPFI | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 12.37 ± 0.0014 µg/ml |
| dbacp07772 | Longicalycinin A cyclic analogue 12 | FYPFI | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 13.2 ± 0 µg/ml |
| dbacp07773 | Longicalycinin A cyclic analogue 12 | FYPFI | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 63.84% Cell death at 100 µg/ml |
| dbacp07774 | Longicalycinin A cyclic analogue 12 | FYPFI | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 52.72% Cell death at 100 µg/ml |
| dbacp07775 | Longicalycinin A cyclic analogue 15 | PYGFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.33 ± 0 µg/ml |
| dbacp07776 | Longicalycinin A cyclic analogue 15 | PYGFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 11.23 ± 0.0007 µg/ml |
| dbacp07777 | Longicalycinin A cyclic analogue 15 | PYGFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 52.33% Cell death at 100 µg/ml |
| dbacp07778 | Longicalycinin A cyclic analogue 15 | PYGFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 27.43% Cell death at 100 µg/ml |
| dbacp07779 | Longicalycinin A linear analogue 16 | FTPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 11.1 ± 0.0007 µg/ml |
| dbacp07780 | Longicalycinin A linear analogue 16 | FTPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 12.11 ± 0.0056 µg/ml |
| dbacp07781 | Longicalycinin A linear analogue 16 | FTPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 15.76% Cell death at 100 µg/ml |
| dbacp07782 | Longicalycinin A linear analogue 16 | FTPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 88.24% Cell death at 100 µg/ml |
| dbacp07783 | Longicalycinin A cyclic analogue 16 | FTPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 12.1 ± 0.0007 µg/ml |
| dbacp07784 | Longicalycinin A cyclic analogue 16 | FTPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.4 ± 0.0028 µg/ml |
| dbacp07785 | Longicalycinin A cyclic analogue 16 | FTPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 42.33% Cell death at 100 µg/ml |
| dbacp07786 | Longicalycinin A cyclic analogue 16 | FTPFV | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 29.87% Cell death at 100 µg/ml |
| dbacp07787 | Longicalycinin A linear analogue 17 | FSPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.33 ± 0.0007 µg/ml |
| dbacp07788 | Longicalycinin A linear analogue 17 | FSPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 11.33 ± 0.0035 µg/ml |
| dbacp07789 | Longicalycinin A linear analogue 17 | FSPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 27.54% Cell death at 100 µg/ml |
| dbacp07790 | Longicalycinin A linear analogue 17 | FSPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 75.68% Cell death at 100 µg/ml |
| dbacp07791 | Longicalycinin A cyclic analogue 17 | FSPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.4 ± 0.0014 µg/ml |
| dbacp07792 | Longicalycinin A cyclic analogue 17 | FSPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 11.2 ± 0.0007 µg/ml |
| dbacp07793 | Longicalycinin A cyclic analogue 17 | FSPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 74.53% Cell death at 100 µg/ml |
| dbacp07794 | Longicalycinin A cyclic analogue 17 | FSPFA | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 76.14% Cell death at 100 µg/ml |
| dbacp07795 | Longicalycinin A linear analogue 18 | FSPAG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 10.33 ± 0.0007 µg/ml |
| dbacp07796 | Longicalycinin A linear analogue 18 | FSPAG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 10.2 ± 0.0014 µg/ml |
| dbacp07797 | Longicalycinin A linear analogue 18 | FSPAG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 15.55% Cell death at 100 µg/ml |
| dbacp07798 | Longicalycinin A linear analogue 18 | FSPAG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | 56.51% Cell death at 100 µg/ml |
| dbacp07799 | Longicalycinin A cyclic analogue 18 | FSPAG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | IC50 = 9.68 ± 0.0014 µg/ml |
| dbacp07800 | Longicalycinin A cyclic analogue 18 | FSPAG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colorectal Cancer | IC50 = 9.06 ± 0.0014 µg/ml |
| dbacp07801 | Longicalycinin A cyclic analogue 18 | FSPAG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HepG-2 | Liver Cancer | 46.58% Cell death at 100 µg/ml |
| dbacp07802 | Longicalycinin A cyclic analogue 18 | FSPAG | Synthetic Analogue of Longicalycinin A | Cyclization enhances apoptosis via lysosomes | MTT assay | HT-29 | Colon Cancer | 22.8% Cell death at 100 µg/ml |
| dbacp07951 | S-24-R2PLx | GIMDTVKNAAKNLAGQLLDKLKCSITAC | Synthetic Analogue of Ranatuerin-2PLx | R2PLx induces caspase-dependent apoptosis | MTT assay | PC-3 | Prostate Cancer | IC50 = 792.60 µM |
| dbacp07952 | S-24-R2PLx | GIMDTVKNAAKNLAGQLLDKLKCSITAC | Synthetic Analogue of Ranatuerin-2PLx | R2PLx induces caspase-dependent apoptosis | MTT assay | H-157 | Lung Cancer | IC50 = 58.18 µM |
| dbacp07953 | S-24-R2PLx | GIMDTVKNAAKNLAGQLLDKLKCSITAC | Synthetic Analogue of Ranatuerin-2PLx | R2PLx induces caspase-dependent apoptosis | MTT assay | MDA-MB-435S | Skin Cancer | IC50 = 179.00 µM |
| dbacp07954 | S-24-R2PLx | GIMDTVKNAAKNLAGQLLDKLKCSITAC | Synthetic Analogue of Ranatuerin-2PLx | R2PLx induces caspase-dependent apoptosis | MTT assay | U-251-MG | Brain Tumor | IC50 = 278.30 µM |
| dbacp07955 | S-24-R2PLx | GIMDTVKNAAKNLAGQLLDKLKCSITAC | Synthetic Analogue of Ranatuerin-2PLx | R2PLx induces caspase-dependent apoptosis | MTT assay | MCF-7 | Breast Cancer | IC50 = 316.90 µM |
| dbacp07993 | [G10a]SHa | FLSGIVGMLaKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | MCF-7 | Breast Cancer | IC50 = 16.2 ± 2.2 µM |
| dbacp07994 | [G10a]SHa | FLSGIVGMLaKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | HeLa | Cervical Cancer | IC50 = 22.7 ± 0.86 µM |
| dbacp07995 | [G10a]SHa | FLSGIVGMLaKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | NCI-H-460 | Lung Cancer | IC50 =24.3 ± 0.8 µM |
| dbacp07996 | [G10a]SHa-BCTP | FLSGIVGMLaKLFLFKQYAELW | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | MCF-7 | Breast Cancer | IC50 = 26.85 ± 1.85 µM |
| dbacp07997 | [G10a]SHa-BCTP | FLSGIVGMLaKLFLFKQYAELW | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | HeLa | Cervical Cancer | IC50 >100 µM |
| dbacp07998 | [G10a]SHa-BCTP | FLSGIVGMLaKLFLFKQYAELW | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | NCI-H-460 | Lung Cancer | IC50 >100 µM |
| dbacp07999 | [G4a]SHa | FLSaIVGMLGKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | MCF-7 | Breast Cancer | IC50 = 17.9 ± 1.1 µM |
| dbacp08000 | [G4a]SHa | FLSaIVGMLGKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | HeLa | Cervical Cancer | IC50 >100 µM |
| dbacp08001 | [G4a]SHa | FLSaIVGMLGKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | NCI-H-460 | Lung Cancer | IC50 >100 µM |
| dbacp08002 | [G7a]SHa | FLSGIVaMLGKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | MCF-7 | Breast Cancer | IC50 =22.4 ± 2.2 µM |
| dbacp08003 | [G7a]SHa | FLSGIVaMLGKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | HeLa | Cervical Cancer | IC50 >100 µM |
| dbacp08004 | [G7a]SHa | FLSGIVaMLGKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | NCI-H-460 | Lung Cancer | IC50 >100 µM |
| dbacp08005 | [G4,7a]SHa | FLSaIVaMLGKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | MCF-7 | Breast Cancer | IC50 = 29.5 ± 6.03 µM |
| dbacp08006 | [G4,7a]SHa | FLSaIVaMLGKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | HeLa | Cervical Cancer | IC50 >100 µM |
| dbacp08007 | [G4,7a]SHa | FLSaIVaMLGKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | NCI-H-460 | Lung Cancer | IC50 = 37.3 ± 3.5 µM |
| dbacp08008 | [G4,7,10a]SHa | FLSaIVaMLaKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | MCF-7 | Breast Cancer | IC50 = 26.33 ± 5.8 µM |
| dbacp08009 | [G4,7,10a]SHa | FLSaIVaMLaKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | HeLa | Cervical Cancer | IC50 >100 µM |
| dbacp08010 | [G4,7,10a]SHa | FLSaIVaMLaKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | NCI-H-460 | Lung Cancer | IC50 >100 µM |
| dbacp08011 | [G7,10a]SHa | FLSGIVaMLaKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | MCF-7 | Breast Cancer | IC50 = 21.3 ± 1.13 µM |
| dbacp08012 | [G7,10a]SHa | FLSGIVaMLaKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | HeLa | Cervical Cancer | IC50 >100 µM |
| dbacp08013 | [G7,10a]SHa | FLSGIVaMLaKLF | Synthetic analogue of Temporin-1SHa | Enhanced cationicity/hydrophobicity increases cytotoxicity | MTT assay | NCI-H-460 | Lung Cancer | IC50 >100 µM |