15 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp02306 | Caspase 3 inhibitor | DEVD | Caspase 3 inhibitor | Cell membrane disruption | MTT/MTS assay | Bcap-37 | Breast cancer | 65% cytotoxicity at 20 µM approx. |
| dbacp02307 | Caspase 3 inhibitor | DEVD | Caspase 3 inhibitor | Cell membrane disruption | MTT/MTS assay | Bcap-37 | Breast cancer | 65% cytotoxicity at 30 µM |
| dbacp02308 | Caspase 3 inhibitor | DEVD | Caspase 3 inhibitor | Cell membrane disruption | MTT/MTS assay | Bcap-37 | Breast cancer | 65% cytotoxicity at 40 µM |
| dbacp04131 | LK1 (Temporin-1CEa Analog peptide) | FVDLKKIANIINSIFKK | Synthetic construct | Cell membrane disintegration | MTT-assay | Bcap-37 | Breast cancer | IC50 : 18.7 µM |
| dbacp04134 | LK2(5) (Temporin-1CEa Analog peptide) | FKDLKKIANIINSIFKK | Synthetic construct | Cell membrane disintegration | MTT-assay | Bcap-37 | Breast cancer | IC50 : 83.49 µM |
| dbacp04137 | LK2(6) (Temporin-1CEa Analog peptide) | FVKLKKIANIINSIFKK | Synthetic construct | Cell membrane disintegration | MTT-assay | Bcap-37 | Breast cancer | IC50 : 18.9 µM |
| dbacp04140 | LK2(6)A(L) (Temporin-1CEa Analog peptide) | FVKLKKILNIINSIFKK | Synthetic construct | Cell membrane disintegration | MTT-assay | Bcap-37 | Breast cancer | IC50 : 10.52 µM |
| dbacp04143 | LK2(6)AN(2L) (Temporin-1CEa Analog peptide) | FVKLKKILNIILSIFKK | Synthetic construct | Cell membrane disintegration | MTT-assay | Bcap-37 | Breast cancer | IC50 : 9.39 µM |
| dbacp04146 | LK3 (Temporin-1CEa Analog peptide) | FKKLKKIANIINSIFKK | Synthetic construct | Cell membrane disintegration | MTT-assay | Bcap-37 | Breast cancer | IC50 : 25.04 µM |
| dbacp06222 | Tempoprin-1CEa | FVDLKKIANIINSIF | Chinese brown frog | Cell membrane disruption | MTT/MTS assay | Bcap-37 | Breast cancer | 70% Cell viability at 20 µM |
| dbacp06223 | Tempoprin-1CEa | FVDLKKIANIINSIF | Chinese brown frog | Cell membrane disruption | MTT/MTS assay | Bcap-37 | Breast cancer | 45% Cell viability at 30 µM |
| dbacp06224 | Tempoprin-1CEa | FVDLKKIANIINSIF | Chinese brown frog | Cell membrane disruption | MTT/MTS assay | Bcap-37 | Breast cancer | 30 % Cell viability at 40 µM |
| dbacp07479 | (LLKK)4 linear peptide | LLKKLLKKLLKKLLKK | Synthetic | Apoptosis, drug-resistance reversal, tumor suppression | MTT assay | Bcap-37 | Breast Cancer | Cell Viability (%) ~ 15.07 ± 0.5 at 30 µg/mL |
| dbacp07483 | 2-arm branched peptide | [LLKKLLKK]2kC | Synthetic | Apoptosis, drug-resistance reversal, tumor suppression | MTT assay | Bcap-37 | Breast Cancer | Cell Viability (%) ~ 81.8 ± 8.8 at 30 µg/mL |
| dbacp07487 | 4-arm branched peptide | {[LLKKLLKK]2kC}2 | Synthetic | Apoptosis, drug-resistance reversal, tumor suppression | MTT assay | Bcap-37 | Breast Cancer | Cell Viability (%) ~ 51.4 ± 4.2 at 30 µg/mL |