24 result(s) have been found!
| Accession | Name | Sequence | Source/Organism | Mechanism | Assay Type | Cell Line | Cancer Type | Activity |
|---|---|---|---|---|---|---|---|---|
| dbacp03124 | Gomesin | GCRRLCYKQRCVTYCRGR | Tarantula spider sp. | Membrane permeabilization | Lactate dehydrogenase (LDH) assay | U-87 MG | Glioblastoma | MIC : 10 mM |
| dbacp04604 | Maximin H1 | ILGPVISTIGGVLGGLLKNL | Yunnan firebelly toad, China, Asia | Not specified | MTT assay | BIU-87 | Bladder cancer | Not found |
| dbacp04609 | Maximin1 | GIGTKILGGVKTALKGALKELASTYAN | Yunnan firebelly toad | Not specified | MTT/MTS assay | BIU-87 | Bladder cancer | IC50 : 20.5 µg/ml |
| dbacp04613 | Maximin3 | GIGGKILSGLKTALKGAAKELASTYLH | Yunnan firebelly toad | Not specified | MTT/MTS assay | BIU-87 | Bladder cancer | IC50 : 28 µg/ml |
| dbacp04617 | Maximin4 | GIGVLLSAGKAALKGLAKVLAEKYAN | Yunnan firebelly toad | Not specified | MTT/MTS assay | BIU-87 | Bladder cancer | IC50 : >50 µg/ml |
| dbacp04621 | Maximin5 | SIGAKILGGVKTFFKGALKELASTYLQ | Yunnan firebelly toad | Not specified | MTT/MTS assay | BIU-87 | Bladder cancer | IC50 : >50 µg/ml |
| dbacp06750 | mPNC-NLS | QETFSDLWKLLVQRKRQKLMP | Synthetic | p53-mediated apoptosis | MTT assay | U-87 | Brain Tumor | IC50 = 56.9 μM |
| dbacp07241 | RB4 | MADSERLSAPGCWAACTNFSRTRK | Derived from protein PLP2 | F-actin modulation induces necrotic death. | MTT assay | U-87 | Brain Tumor | EC50 = 0.427 ± 0.053 mol/L × 10-3 |
| dbacp07439 | A4K14 - Citropin 1.1 - Sp 7 | GLFAVR8KKVASVS5KGL | Synthetic | Stapled peptide enhances helical apoptosis | CCK-8 assay | U-87 | Brain Tumor | IC50 = 14.72 µM |
| dbacp07443 | A4K14 - Citropin 1.1 - Sp 6 | GR8FAVIKKS5ASVIKGL | Synthetic | Stapled peptide enhances helical apoptosis | CCK-8 assay | U-87 | Brain Tumor | IC50 = 34.49 µM |
| dbacp07447 | A4K14 - Citropin 1.1 - Sp 5 | GLFAVIKKVAS5VIKS5L | Synthetic | Stapled peptide enhances helical apoptosis | CCK-8 assay | U-87 | Brain Tumor | IC50 = 8.229 µM |
| dbacp07451 | A4K14 - Citropin 1.1 - Sp 4 | GLFAVIKKS5ASVS5KGL | Synthetic | Stapled peptide enhances helical apoptosis | CCK-8 assay | U-87 | Brain Tumor | IC50 = 7.277 µM |
| dbacp07455 | A4K14 - Citropin 1.1 - Sp 3 | GLFAVS5KKVS5SVIKGL | Synthetic | Stapled peptide enhances helical apoptosis | CCK-8 assay | U-87 | Brain Tumor | IC50 = 11.93 µM |
| dbacp07459 | A4K14 - Citropin 1.1 - Sp 2 | GLFAS5IKKS5ASVIKGL | Synthetic | Stapled peptide enhances helical apoptosis | CCK-8 assay | U-87 | Brain Tumor | IC50 = 14.76 µM |
| dbacp07463 | A4K14 - Citropin 1.1 - Sp 1 | GS5FAVS5KKVASVIKGL | Synthetic | Stapled peptide enhances helical apoptosis | CCK-8 assay | U-87 | Brain Tumor | IC50 = 11.88 µM |
| dbacp07649 | AP1-Z1 | FLFSLIPHAISGLISAFK | AcrAP1 from the venom of the Arabian scorpion | Charge–hydrophobicity balance drives apoptosis | MTT assay | U-87 | Brain Tumor | IC50 = 10.21 μM |
| dbacp07652 | AP1-Z5a | FLFKLIPKAIKGLIKAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | U-87 | Brain Tumor | Graph Figure 2C |
| dbacp07655 | AP1-Z5b | FLFKLIKHAIKGLIKAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | U-87 | Brain Tumor | IC50 = 3.115 μM |
| dbacp07658 | AP1-Z3a | FLFSLIKHAIKGLISAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | U-87 | Brain Tumor | Graph Figure 2C |
| dbacp07661 | AP1-Z3b | FLFSLIKHAISKLISAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | U-87 | Brain Tumor | Graph Figure 2C |
| dbacp07664 | AP1-Z7 | FLFKLIKKAIKKLIKAFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | U-87 | Brain Tumor | Graph Figure 2C |
| dbacp07667 | AP1-Z9 | FLFKLIKKKIKKLIKKFK | Mutant of APR-Z1 | Charge–hydrophobicity balance drives apoptosis | MTT assay | U-87 | Brain Tumor | Graph Figure 2C |
| dbacp07934 | LyeTx-I-b | IWLTALKFLGKNLGKLAKQQLAKL | Synthetic | Membrane disruption, necroptosis, limited apoptosis | MTT/Resazurin dye assay | U-87-MG | Brain Tumor | IC50 = 29.20 ± 7.96 µM |
| dbacp07949 | IL13Rα2 D1 peptide | GSETWKTIITKN | Synthetic | IL13Rα2 blockade inhibits cancer metastasis | MTT assay | U-87 | Brain Cancer | inhibited IL13-stimulated cell adhesion |